CCR10 and CCL27

Number of citations of the paper that reports this interaction (PMID 11821900)
79

Data Source:
HPRD (in vivo)

		CCR10	CCL27
Gene Name		chemokine (C-C motif) receptor 10	chemokine (C-C motif) ligand 27
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Extracellular Region Extracellular Space
	Molecular Function	G-protein Coupled Receptor Activity C-C Chemokine Receptor Activity	Chemokine Activity
	Biological Process	Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine-mediated Signaling Pathway	Chemotaxis Immune Response Cell-cell Signaling Cell Chemotaxis
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CCL19 CCL2 CCL21 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A	2 interactors: ACKR2 CCR10
Entrez ID		2826	10850
HPRD ID		02586	05321
Ensembl ID			ENSG00000213927
Uniprot IDs		P46092	Q5VZ77 Q9Y4X3
PDB IDs			2KUM
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Regulation Of Leukocyte Migration Chemotaxis Positive Regulation Of Leukocyte Chemotaxis Cell Migration Positive Regulation Of Leukocyte Migration Cell Motility Leukocyte Migration Leukocyte Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Cell Migration Cellular Calcium Ion Homeostasis Positive Regulation Of Behavior Calcium Ion Homeostasis Regulation Of Cell Motility Regulation Of Chemotaxis Locomotion Regulation Of Locomotion Immune Response Regulation Of Cellular Component Movement Positive Regulation Of Cell Adhesion Cellular Metal Ion Homeostasis Movement Of Cell Or Subcellular Component Regulation Of Behavior Inflammatory Response Cellular Cation Homeostasis Regulation Of Dendritic Cell Dendrite Assembly Cellular Ion Homeostasis Metal Ion Homeostasis Negative Regulation Of Leukocyte Migration Cellular Chemical Homeostasis Response To External Stimulus Negative Regulation Of Leukocyte Tethering Or Rolling Ion Homeostasis Regulation Of Cell Adhesion Regulation Of Lymphocyte Migration Immune System Process Regulation Of Granulocyte Chemotaxis Positive Regulation Of Cell Migration Establishment Of T Cell Polarity Positive Regulation Of Cell Motility Cellular Homeostasis Regulation Of Immune System Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Cell-cell Adhesion Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Chemical Homeostasis Positive Regulation Of Cell-matrix Adhesion	Neutrophil Activation Chemokine-mediated Signaling Pathway Receptor-mediated Endocytosis Inflammatory Response Cytokine-mediated Signaling Pathway Leukocyte Activation Cellular Response To Cytokine Stimulus Chemotaxis Endocytosis Cell Activation Response To Cytokine G-protein Coupled Receptor Signaling Pathway Locomotion Immune Response Defense Response Vesicle-mediated Transport Response To External Stimulus Cellular Response To Organic Substance Immune System Process Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Cell Surface Receptor Signaling Pathway Response To Stress Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis
Tagcloud ?		allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes	classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate
Tagcloud (Difference) ?		allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes	classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate
Tagcloud (Intersection) ?