CCR10 and CCL7

Number of citations of the paper that reports this interaction (PubMedID 9364936)
0

Data Source:
HPRD (in vivo)

		CCR10	CCL7
Description		C-C motif chemokine receptor 10	C-C motif chemokine ligand 7
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Extracellular Region Extracellular Space
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CCR1 Chemokine Receptor Binding CCR2 Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Monocyte Chemotaxis Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Cytoskeleton Organization Signal Transduction Canonical NF-kappaB Signal Transduction Cell-cell Signaling Regulation Of Cell Shape Response To Gamma Radiation Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of Cell Migration Eosinophil Chemotaxis Positive Regulation Of Inflammatory Response Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Ethanol Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Crohn's disease ( 21102463 22412388 28067908) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908)
Interacting Genes		10 interacting genes: ARPC3 CCL19 CCL2 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A	18 interacting genes: ACKR1 ACKR2 ACKR4 CCR1 CCR10 CCR3 CCR5 CXCL6 FEZ1 MMP1 MMP13 MMP14 MMP2 MMP3 TLE5 UBQLN1 UBQLN2 XCL2
Entrez ID		2826	6354
HPRD ID		02586	01150
Ensembl ID		ENSG00000184451	ENSG00000108688
Uniprot IDs		P46092	P80098
PDB IDs			1BO0 1NCV 4ZKC 7S58 7S59 7SCU 8FJ3 8FK6 8FK8 8JPS
Enriched GO Terms of Interacting Partners?		Chemokine Activity Myeloid Leukocyte Migration Leukocyte Chemotaxis Granulocyte Chemotaxis Granulocyte Migration Cell Chemotaxis Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Chemotaxis Chemokine-mediated Signaling Pathway Locomotion Cytokine Activity Regulation Of Leukocyte Migration Chemokine Receptor Binding Humoral Immune Response Inflammatory Response CCR10 Chemokine Receptor Binding Eosinophil Chemotaxis Cell Motility Eosinophil Migration CCR Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Mononuclear Cell Migration Cell Migration Killing Of Cells Of Another Organism Positive Regulation Of Chemotaxis Positive Regulation Of Leukocyte Migration CXCR Chemokine Receptor Binding Cell Killing Immune Response Cytokine-mediated Signaling Pathway Defense Response To Symbiont Defense Response To Other Organism Regulation Of Chemotaxis Response To External Biotic Stimulus Cellular Response To Lipid Defense Response Cellular Response To Oxygen-containing Compound Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Positive Regulation Of Mononuclear Cell Migration CCL19-activated CCR7 Signaling Pathway Regulation Of Lymphocyte Chemotaxis Positive Regulation Of Cell Migration Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Cell Motility Response To Lipopolysaccharide	Chemokine-mediated Signaling Pathway C-C Chemokine Binding Chemokine Receptor Activity C-C Chemokine Receptor Activity Cell Chemotaxis Chemotaxis Locomotion Cytokine-mediated Signaling Pathway Collagen Catabolic Process Extracellular Matrix Disassembly Collagen Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Migration Cell Surface Receptor Signaling Pathway Calcium-mediated Signaling Endopeptidase Activity Metalloendopeptidase Activity Cell Motility G Protein-coupled Receptor Signaling Pathway Cellular Response To UV-A G Protein-coupled Receptor Activity Metallopeptidase Activity Response To UV-A Serine-type Endopeptidase Activity Chemokine (C-C Motif) Ligand 5 Binding Inflammatory Response Immune System Process External Side Of Plasma Membrane Immune Response Response To Stress Extracellular Structure Organization Extracellular Matrix Organization Leukocyte Chemotaxis Chemokine Binding Intracellular Signaling Cassette Response To Amyloid-beta Defense Response Extracellular Matrix Leukocyte Migration Peptidase Activity Cellular Response To UV Signal Transduction Dendritic Cell Chemotaxis Positive Regulation Of ERAD Pathway Mononuclear Cell Migration Proteolysis Cellular Response To Light Stimulus Plasma Membrane Response To Cytokine Dendritic Cell Migration
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