CCL25 and PF4V1

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down, pull down)

		CCL25	PF4V1
Description		C-C motif chemokine ligand 25	platelet factor 4 variant 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Immune System Process Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Eosinophil Chemotaxis Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Negative Regulation Of Leukocyte Tethering Or Rolling	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399)	Inflammatory bowel disease ( 23128233)
Interacting Genes		11 interacting genes: ACKR2 ACKR4 CCL17 CCL5 CCR10 CCR9 CXCL11 CXCL12 CXCL17 PF4 PF4V1	15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Entrez ID		6370	5197
HPRD ID		03976	01427
Ensembl ID		ENSG00000131142	ENSG00000109272
Uniprot IDs		O15444	P10720
PDB IDs			4HSV
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Chemotaxis Locomotion Chemokine-mediated Signaling Pathway Cell Migration Chemokine Activity Cell Motility Cytokine-mediated Signaling Pathway Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Immune Response Leukocyte Chemotaxis Immune System Process Antimicrobial Humoral Response Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Cytokine Activity Leukocyte Migration Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Humoral Immune Response CXCR Chemokine Receptor Binding Positive Regulation Of Monocyte Chemotaxis Defense Response Inflammatory Response Extracellular Space Killing Of Cells Of Another Organism Regulation Of Monocyte Chemotaxis Myeloid Leukocyte Migration External Side Of Plasma Membrane Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling CXCR3 Chemokine Receptor Binding Defense Response To Symbiont Defense Response To Other Organism Cell Killing Cell Surface Receptor Signaling Pathway Granulocyte Chemotaxis Chemokine Receptor Binding Granulocyte Migration Signal Transduction Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Transport Response To Other Organism T Cell Chemotaxis Macrophage Chemotaxis Positive Regulation Of Macrophage Chemotaxis G Protein-coupled Receptor Activity Macrophage Migration	Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Humoral Immune Response Granulocyte Chemotaxis Chemotaxis Locomotion Leukocyte Migration Granulocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration CCR Chemokine Receptor Binding Cell Killing Defense Response To Symbiont Defense Response To Other Organism Chemokine Receptor Binding Inflammatory Response Cell Migration Cytokine-mediated Signaling Pathway Cell Motility Response To Other Organism Immune Response Eosinophil Chemotaxis Eosinophil Migration Response To External Biotic Stimulus Defense Response Extracellular Space G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Immune System Process Regulation Of Cell Migration Regulation Of Cell Motility Mononuclear Cell Migration Regulation Of Locomotion Extracellular Region Lymphocyte Chemotaxis CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Lymphocyte Migration Regulation Of Leukocyte Migration Response To Stress Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Extravasation Cell Surface Receptor Signaling Pathway
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