CCR10 and CCL28

Number of citations of the paper that reports this interaction (PubMedID 10781587)
0

Data Source:
HPRD (in vitro)

		CCR10	CCL28
Description		C-C motif chemokine receptor 10	C-C motif chemokine ligand 28
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Extracellular Region Extracellular Space Secretory Granule Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding	Cytokine Activity Protein Binding Chemokine Activity Chemokine Receptor Binding CXCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Inflammatory Response Immune Response Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Neutrophil Chemotaxis Killing Of Cells Of Another Organism Cytolysis In Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS			Metabolite levels (X-11787) ( 23934736) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		10 interacting genes: ARPC3 CCL19 CCL2 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A	26 interacting genes: ACKR2 CCL11 CCL13 CCL17 CCL21 CCL26 CCL5 CCR10 CCR3 CXCL10 CXCL12 CXCL13 CXCL14 CXCL17 CXCL2 CXCL9 DDI1 DYNLT3 PF4 PF4V1 PPBP PSMA3 STUB1 TSC1 XCL1 XCL2
Entrez ID		2826	56477
HPRD ID		02586	05577
Ensembl ID		ENSG00000184451	ENSG00000151882
Uniprot IDs		P46092	A0N0Q3 D6RC73 Q9NRJ3
PDB IDs			6CWS
Enriched GO Terms of Interacting Partners?		Chemokine Activity Myeloid Leukocyte Migration Leukocyte Chemotaxis Granulocyte Chemotaxis Granulocyte Migration Cell Chemotaxis Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Chemotaxis Chemokine-mediated Signaling Pathway Locomotion Cytokine Activity Regulation Of Leukocyte Migration Chemokine Receptor Binding Humoral Immune Response Inflammatory Response CCR10 Chemokine Receptor Binding Eosinophil Chemotaxis Cell Motility Eosinophil Migration CCR Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Mononuclear Cell Migration Cell Migration Killing Of Cells Of Another Organism Positive Regulation Of Chemotaxis Positive Regulation Of Leukocyte Migration CXCR Chemokine Receptor Binding Cell Killing Immune Response Cytokine-mediated Signaling Pathway Defense Response To Symbiont Defense Response To Other Organism Regulation Of Chemotaxis Response To External Biotic Stimulus Cellular Response To Lipid Defense Response Cellular Response To Oxygen-containing Compound Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Positive Regulation Of Mononuclear Cell Migration CCL19-activated CCR7 Signaling Pathway Regulation Of Lymphocyte Chemotaxis Positive Regulation Of Cell Migration Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Cell Motility Response To Lipopolysaccharide	Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Chemokine-mediated Signaling Pathway Cytokine Activity Humoral Immune Response Leukocyte Chemotaxis Cell Migration Granulocyte Chemotaxis Killing Of Cells Of Another Organism Cell Motility Myeloid Leukocyte Migration Granulocyte Migration Immune Response Leukocyte Migration Inflammatory Response Cell Killing Cytokine-mediated Signaling Pathway Immune System Process Defense Response To Symbiont CXCR Chemokine Receptor Binding Defense Response To Other Organism Defense Response CCR Chemokine Receptor Binding Response To Other Organism G Protein-coupled Receptor Signaling Pathway Mononuclear Cell Migration Extracellular Space Response To External Biotic Stimulus Neutrophil Chemotaxis Neutrophil Migration Response To Stress Positive Regulation Of T Cell Migration Regulation Of T Cell Chemotaxis Extracellular Region CXCR3 Chemokine Receptor Binding Positive Regulation Of Chemotaxis Positive Regulation Of Lymphocyte Migration Positive Regulation Of Leukocyte Chemotaxis Eosinophil Chemotaxis Positive Regulation Of Mononuclear Cell Migration Regulation Of T Cell Migration Eosinophil Migration Positive Regulation Of Cell Migration Regulation Of Lymphocyte Chemotaxis Lymphocyte Chemotaxis Signal Transduction
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