IL11 and IL11RA

Number of citations of the paper that reports this interaction (PMID 10504396)
5

Data Source:
HPRD (in vivo, in vitro)

		IL11	IL11RA
Gene Name		interleukin 11	interleukin 11 receptor, alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Integral Component Of Plasma Membrane
	Molecular Function	Cytokine Activity Interleukin-11 Receptor Binding Growth Factor Activity	Signal Transducer Activity Transmembrane Signaling Receptor Activity Cytokine Receptor Activity
	Biological Process	Cell-cell Signaling Positive Regulation Of Cell Proliferation B Cell Differentiation Megakaryocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAPK Cascade Fat Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Hormone Secretion Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Endothelial Cell Apoptotic Process	Signal Transduction Embryo Implantation Cytokine-mediated Signaling Pathway Developmental Process Head Development
Pathways
Drugs			Oprelvekin
Diseases
GWAS		Response to antidepressants ( 20360315)
Protein-Protein Interactions		2 interactors: IL11RA MAGEA11	1 interactors: IL11
Entrez ID		3589	3590
HPRD ID		00980	02965
Ensembl ID		ENSG00000095752	ENSG00000137070
Uniprot IDs		A8K3F7 P20809	Q14626 Q5VZ79
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		activate bases cardiotrophin ciliary cloned cloning conferred cos counterpart epo erythropoietin gm il2 il3 il6 immediate kinetics lif lymphoid murine neurotrophic oncostatin osm possesses reaching stat5 subfamily subset thereafter	bioinformatics bmp2 calm1 cnaq csf2rb csf3 expressions fifteen gria2 il10rb il3ra il6st lifr lymphatic microarrays myl9 mylk myosin nonsmokers nsclc paraneoplastic pathohistological plcb4 ppp2ca rac3 rock2 thbs1 verify
Tagcloud (Difference) ?		activate bases cardiotrophin ciliary cloned cloning conferred cos counterpart epo erythropoietin gm il2 il3 il6 immediate kinetics lif lymphoid murine neurotrophic oncostatin osm possesses reaching stat5 subfamily subset thereafter	bioinformatics bmp2 calm1 cnaq csf2rb csf3 expressions fifteen gria2 il10rb il3ra il6st lifr lymphatic microarrays myl9 mylk myosin nonsmokers nsclc paraneoplastic pathohistological plcb4 ppp2ca rac3 rock2 thbs1 verify
Tagcloud (Intersection) ?