CLIP1 and TUBB

Number of citations of the paper that reports this interaction (PMID 16455083)
13

Data Source:
BioGRID (pull down)

		CLIP1	TUBB
Gene Name		CAP-GLY domain containing linker protein 1	tubulin, beta class I
Image
Gene Ontology Annotations	Cellular Component	Kinetochore Ruffle Cytoplasm Endosome Centrosome Cytosol Microtubule Cytoplasmic Microtubule Intermediate Filament Microtubule Cytoskeleton Cytoplasmic Vesicle Membrane Microtubule Plus-end Macropinosome	Nucleus Nuclear Envelope Lumen Cytosol Cytoskeleton Microtubule Cytoplasmic Ribonucleoprotein Granule Cell Body Extracellular Vesicular Exosome
	Molecular Function	Nucleic Acid Binding Protein Binding Microtubule Binding Zinc Ion Binding Tubulin Binding Protein Homodimerization Activity Metal Ion Binding Microtubule Plus-end Binding	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Complex Binding GTPase Activating Protein Binding MHC Class I Protein Binding
	Biological Process	Mitotic Cell Cycle Microtubule Bundle Formation Mitotic Nuclear Division Positive Regulation Of Microtubule Polymerization Protein Transport Into Plasma Membrane Raft	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Movement Of Cell Or Subcellular Component Organelle Organization Microtubule-based Process Cellular Process Cytoskeleton-dependent Intracellular Transport Natural Killer Cell Mediated Cytotoxicity Spindle Assembly Protein Polymerization Cell Division
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs			Vinorelbine Vincristine Vinblastine Podofilox Colchicine Epothilone D Epothilone B
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CALM1 CLASP2 DCTN1 IQGAP1 MAPRE1 MAPRE2 MTOR PAFAH1B1 TUBA1A TUBB	61 interactors: ALDOA APP ARL8B ATXN3 B4GALT1 BMPR2 BRCA1 CCT2 CDKN2A CLIP1 CMTM5 CNN1 CRIPT DISC1 DPYSL2 DYNLL1 ESR1 GDAP1 GNB2L1 GRM1 HDAC6 HGS HTRA2 HTT MAGEA2B MAL2 MAP1A MAP3K10 MAP4 MAP6 MAPRE1 MAPT MARK4 MRGBP MX1 NCALD NCAM1 NPHP1 PARK2 PFDN4 PLK1 RAB8B RASSF1 SDC3 SIRT2 SPP1 STAU1 SYT9 TAOK2 TBCD TGM2 TINF2 TTBK1 TTK TUBA1A VAV1 YWHAB YWHAG YWHAQ YWHAZ ZAP70
Entrez ID		6249	203068
HPRD ID		01568	01852
Ensembl ID		ENSG00000130779	ENSG00000196230
Uniprot IDs		B3KXA5 P30622	B4DMJ5 P07437 Q5ST81 Q5SU16
PDB IDs		2CP5 2CP6 2E3H 2E3I 2E4H 2HQH 2QK0 3E2U 3RDV	3QNZ 3QO0
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Division Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Cytoskeleton-dependent Intracellular Transport Cell Cycle Organelle Organization Microtubule-based Process Cellular Localization Protein Polymerization Microtubule Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Phosphorus Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Cellular Protein Complex Assembly Positive Regulation Of Protein Modification Process Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Carbohydrate Utilization Cellular Response To Organic Substance Regulation Of Protein Phosphorylation Establishment Of Localization In Cell Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Cytoskeleton Organization Cell Projection Organization Positive Regulation Of Kinase Activity Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Immune System Process Response To Calcium Ion Positive Regulation Of Protein Metabolic Process Regulation Of Ras GTPase Activity Microtubule-based Transport Positive Regulation Of Microtubule Plus-end Binding Establishment Of Centrosome Localization Regulation Of Dephosphorylation	Regulation Of Cellular Component Organization Organelle Organization Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cytoskeleton Organization Microtubule Cytoskeleton Organization Positive Regulation Of Signal Transduction Cellular Localization Microtubule-based Process Regulation Of Organelle Organization Positive Regulation Of Apoptotic Process Programmed Cell Death Positive Regulation Of Organelle Organization Regulation Of Cell Death Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Process Cellular Response To Stimulus Regulation Of Cellular Process Cell Communication Cellular Protein Localization Regulation Of Cellular Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Signaling Regulation Of Apoptotic Process Positive Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intracellular Signal Transduction Response To Stimulus Regulation Of Signal Transduction Cell Cycle Signal Transduction Cell Cycle Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Microtubule-based Process Negative Regulation Of Protein Metabolic Process Mitotic Cell Cycle Nervous System Development Regulation Of Protein Localization
Tagcloud ?		clasp1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus	3p ahi1 annotation clustering datasets demyelinating differential dqb1 dra eqtl eqtls grail highlighted hla loci ms ndfip1 publically relevance rs1062158 rs11154801 rs2647046 rs3095329 rs7194 rs9469220 snps tf trait utilizing
Tagcloud (Difference) ?		clasp1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus	3p ahi1 annotation clustering datasets demyelinating differential dqb1 dra eqtl eqtls grail highlighted hla loci ms ndfip1 publically relevance rs1062158 rs11154801 rs2647046 rs3095329 rs7194 rs9469220 snps tf trait utilizing
Tagcloud (Intersection) ?