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TUBB and MAGEA2B
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid)
TUBB
MAGEA2B
Description
tubulin beta class I
MAGE family member A2B
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nuclear Envelope Lumen
Cytoplasm
Cytosol
Cytoskeleton
Microtubule
Microtubule Cytoskeleton
Protein-containing Complex
Azurophil Granule Lumen
Cytoplasmic Ribonucleoprotein Granule
Cell Body
Membrane Raft
Intercellular Bridge
Extracellular Exosome
Mitotic Spindle
Nucleus
PML Body
Molecular Function
Nucleotide Binding
GTPase Activity
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
GTPase Activating Protein Binding
MHC Class I Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Histone Deacetylase Binding
DNA-binding Transcription Factor Binding
Biological Process
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule-based Process
Cytoskeleton-dependent Intracellular Transport
Natural Killer Cell Mediated Cytotoxicity
Regulation Of Synapse Organization
Spindle Assembly
Cell Division
Odontoblast Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Protein Catabolic Process
Negative Regulation Of Protein Sumoylation
Positive Regulation Of Ubiquitin-protein Transferase Activity
Signal Transduction By P53 Class Mediator
Cellular Senescence
Negative Regulation Of Protein Acetylation
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Neutrophil degranulation
AURKA Activation by TPX2
Potential therapeutics for SARS
Drugs
Vinorelbine
Vincristine
Vinblastine
Podofilox
Colchicine
Epothilone D
Patupilone
CYT997
CA4P
ZEN-012
Tirbanibulin
Copper
Artenimol
Vinflunine
Depatuxizumab mafodotin
Milataxel
Colchiceine
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils) (
30958311
)
Handedness (non-right-handed vs right-handed) (
31504236
)
Left-handedness (
32989287
)
Left–right brain asymmetry (
33723403
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
84 interacting genes:
ADAP2
ALDOA
APP
ARL8B
ATXN3
B4GALT1
BCL2L13
BMPR2
BRCA1
CDK1
CDKN2A
CLIP1
CMTM5
CNN1
CREBBP
CRIPT
DISC1
DPYSL2
DUX4
DYNLL1
EML4
ESR1
FXR1
GDAP1
GRM1
HDAC6
HGS
HTRA2
HTT
LINC01554
LNX2
MAGEA2B
MAL2
MAP1A
MAP3K10
MAP4
MAP6
MAPRE1
MAPT
MARK4
MRGBP
MTNR1A
MX1
NCALD
NCAM1
NCAPH2
NDEL1
NPHP1
OGT
PFDN4
PLK1
PRKN
PRMT1
PTEN
RAB8B
RACK1
RASSF1
RSPH1
S100A8
S100A9
SDC3
SPP1
STAU1
SUMO2
SYT9
TAOK2
TBCD
TBKBP1
TGM2
TINF2
TPPP
TTBK1
TTK
TUBA1A
UBE3A
USP25
VAV1
YWHAB
YWHAG
YWHAQ
YWHAZ
ZAP70
ZFYVE21
ZMYND19
24 interacting genes:
ACSM1
ANKRD45
BEX1
BEX2
CCDC185
CEP57
CEP57L1
COQ4
COX7C
DYNLRB1
KRT8P12
MBD3
NTAQ1
P4HA3
PHKG2
POLL
PSMC1
SEPTIN5
SMARCD1
TNIP3
TRIM28
TRIM31
TUBB
ZNF655
Entrez ID
203068
266740
HPRD ID
01852
14347
Ensembl ID
ENSG00000196230
ENSG00000183305
Uniprot IDs
B4DMJ5
B4DQN9
B4DY90
P07437
Q5ST81
Q5SU16
P43356
PDB IDs
3QNZ
3QO0
5N5N
6I2I
6QUS
6QUY
6QVE
6QVJ
7TRG
7TTN
7TTT
7TUB
7X0S
8BPO
8T42
8U3Z
8V2J
9BP6
Enriched GO Terms of Interacting Partners
?
Microtubule-based Process
Microtubule Cytoskeleton Organization
Organelle Organization
Microtubule Binding
Microtubule
Regulation Of Cellular Component Organization
Cytoskeleton Organization
Microtubule Polymerization
Tubulin Binding
Identical Protein Binding
Microtubule Cytoskeleton
Microtubule Associated Complex
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Microtubule Polymerization Or Depolymerization
Cytoskeleton
Cytosol
Neuron Projection
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Beta-tubulin Binding
Regulation Of Organelle Organization
Cytoplasm
Cytoskeleton-dependent Intracellular Transport
Protein Polymerization
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Proteolysis
Axon
Protein Localization To Organelle
Transport Along Microtubule
Regulation Of Protein Localization
Supramolecular Fiber Organization
Positive Regulation Of Cellular Component Organization
Regulation Of Signaling
Regulation Of Cell Communication
Positive Regulation Of Signal Transduction
Regulation Of Growth
Regulation Of Cellular Response To Stress
Apoptotic Process
Dendrite
Alpha-tubulin Binding
Regulation Of Microtubule-based Process
Tau Protein Binding
Synapse
Programmed Cell Death
Cell Death
Microtubule-based Transport
Regulation Of Microtubule Cytoskeleton Organization
Axo-dendritic Transport
Regulation Of Intracellular Signal Transduction
Cilium Disassembly
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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