RETREG1 and BDKRB1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		RETREG1	BDKRB1
Description		reticulophagy regulator 1	bradykinin receptor B1
Image
GO Annotations	Cellular Component	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cis-Golgi Network Membrane Nuclear Body	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding Endoplasmic Reticulum-autophagosome Adaptor Activity	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Mitophagy Autophagy Endoplasmic Reticulum Organization Sensory Perception Of Pain Collagen Catabolic Process Negative Regulation Of Neuron Apoptotic Process White Fat Cell Differentiation Reticulophagy Substrate Localization To Autophagosome	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs			Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Diffusing capacity of carbon monoxide ( 30694715) Orofacial cleft x maternal periconceptional multivitamin use interaction (1df) ( 33937227)	Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: AMFR APP BDKRB1 GABARAPL2 MAP1LC3B MORC3 SNAPIN	32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		54463	623
HPRD ID		07879	02639
Ensembl ID		ENSG00000154153	ENSG00000100739
Uniprot IDs		A0A804HHX5 Q9H6L5	P46663
PDB IDs		7BRQ 7FB5	7EIB
Enriched GO Terms of Interacting Partners?		Autophagosome Maturation Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Protein-containing Complex Disassembly Vacuole Organization Response To Stress Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cytoplasmic Vesicle Mitophagy Autophagosome Membrane Autophagy Of Mitochondrion SNARE Binding Positive Regulation Of Late Endosome To Lysosome Transport Axo-dendritic Transport Autophagosome Protein-folding Chaperone Binding Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Bradykinin Receptor Activity Autophagosome Organization Autophagosome Assembly Golgi Apparatus PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Phospholipid Binding Negative Regulation Of Canonical Wnt Signaling Pathway Protein-containing Complex Organization Growth Cone BAT3 Complex Binding Regulation Of Calcium Ion Transmembrane Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Positive Regulation Of Leukocyte Migration Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Endoplasmic Reticulum Negative Regulation Of Wnt Signaling Pathway	Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding
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