SLC39A14 and BDKRB1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		SLC39A14	BDKRB1
Description		solute carrier family 39 member 14	bradykinin receptor B1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Early Endosome Membrane Late Endosome Membrane	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Iron Ion Transmembrane Transporter Activity Manganese Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transporter Activity Protein Binding Cadmium Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Monoatomic Anion:monoatomic Cation Symporter Activity Metal Ion Transmembrane Transporter Activity Monoatomic Cation:bicarbonate Symporter Activity	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Chondrocyte Differentiation Gluconeogenesis Monoatomic Ion Transport Iron Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Insulin Receptor Signaling Pathway Regulation Of Hormone Levels Bicarbonate Transport Metal Ion Transport Intracellular Monoatomic Cation Homeostasis Cellular Response To Insulin Stimulus Iron Import Into Cell Iron Ion Transmembrane Transport Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Manganese Ion Homeostasis Transmembrane Transport Cadmium Ion Transmembrane Transport Cellular Response To Glucose Stimulus Manganese Ion Transmembrane Transport Zinc Ion Transmembrane Transport Zinc Ion Import Across Plasma Membrane Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport Import Across Plasma Membrane	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Zinc influx into cells by the SLC39 gene family	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs			Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio ( 29237677) Verbal declarative memory ( 25648963)	Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: BDKRB1 LZTS2 SEPTIN3	32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		23516	623
HPRD ID		12288	02639
Ensembl ID		ENSG00000104635	ENSG00000100739
Uniprot IDs		A0A0S2Z534 Q15043	P46663
PDB IDs			7EIB
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Cytokinesis Primary Ureteric Bud Growth Bradykinin Receptor Activity N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Lactose Synthase Activity Galactosyltransferase Activity Ureter Morphogenesis Microtubule Severing Cerebellar Purkinje Cell Layer Development Septin Ring Septin Complex Spindle Midzone Assembly Cell Division Site Cell Division	Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding
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