SLC39A14 and SEPTIN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC39A14	SEPTIN3
Description		solute carrier family 39 member 14	septin 3
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Early Endosome Membrane Late Endosome Membrane	Cytoplasm Cytoskeleton Septin Ring Microtubule Cytoskeleton Septin Complex Cell Division Site Synapse Presynapse
	Molecular Function	Iron Ion Transmembrane Transporter Activity Manganese Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transporter Activity Protein Binding Cadmium Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Monoatomic Anion:monoatomic Cation Symporter Activity Metal Ion Transmembrane Transporter Activity Monoatomic Cation:bicarbonate Symporter Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity
	Biological Process	Chondrocyte Differentiation Gluconeogenesis Monoatomic Ion Transport Iron Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Insulin Receptor Signaling Pathway Regulation Of Hormone Levels Bicarbonate Transport Metal Ion Transport Intracellular Monoatomic Cation Homeostasis Cellular Response To Insulin Stimulus Iron Import Into Cell Iron Ion Transmembrane Transport Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Manganese Ion Homeostasis Transmembrane Transport Cadmium Ion Transmembrane Transport Cellular Response To Glucose Stimulus Manganese Ion Transmembrane Transport Zinc Ion Transmembrane Transport Zinc Ion Import Across Plasma Membrane Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport Import Across Plasma Membrane	Intracellular Protein Localization Cell Division Cytoskeleton-dependent Cytokinesis
Pathways		Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio ( 29237677) Verbal declarative memory ( 25648963)
Interacting Genes		3 interacting genes: BDKRB1 LZTS2 SEPTIN3	23 interacting genes: CDC37 CHRM3 CKS1B CREBBP DDIT4L EIF6 GABARAPL2 LASP1 MAP1LC3B MAPK6 MOB1A NTAQ1 PELI2 PRKG1 RNF4 RNF8 RSPH1 SDCBP SELENOF SEPTIN1 SLC39A14 SNCA WBP2
Entrez ID		23516	55964
HPRD ID		12288	10515
Ensembl ID		ENSG00000104635	ENSG00000100167
Uniprot IDs		A0A0S2Z534 Q15043	A0A2R8Y4H2 Q9UH03
PDB IDs			3SOP 4Z51 4Z54 6UQQ
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Cytokinesis Primary Ureteric Bud Growth Bradykinin Receptor Activity N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Lactose Synthase Activity Galactosyltransferase Activity Ureter Morphogenesis Microtubule Severing Cerebellar Purkinje Cell Layer Development Septin Ring Septin Complex Spindle Midzone Assembly Cell Division Site Cell Division	Cytoplasm Cytosol Mitophagy Cellular Response To Nitrogen Starvation Regulation Of Phosphorus Metabolic Process Autophagy Of Mitochondrion Phosphatidylethanolamine Binding Meiotic Spindle Ubiquitin-ubiquitin Ligase Activity Protein Modification Process Regulation Of Glutamate Secretion Sperm DNA Condensation Autophagosome Assembly Autophagosome Organization Cellular Response To Nutrient Levels Protein K48-linked Ubiquitination Intracellular Signaling Cassette Intracellular Signal Transduction Regulation Of Secretion By Cell Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Assembly Of Large Subunit Precursor Of Preribosome Regulation Of Ketone Metabolic Process Protein K6-linked Ubiquitination Protein Polyubiquitination Interleukin-5 Receptor Complex Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Protein Catabolic Process Phospholipid Binding Ubiquitin Protein Ligase Binding FMN Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FAD Transmembrane Transport Monoatomic Anion:monoatomic Cation Symporter Activity Protein-N-terminal Glutamine Amidohydrolase Activity
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