MRPL12 and POLR1D

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MRPL12	POLR1D
Gene Name		mitochondrial ribosomal protein L12	polymerase (RNA) I polypeptide D, 16kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit	Nucleoplasm DNA-directed RNA Polymerase III Complex DNA-directed RNA Polymerase I Complex Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Polymerase I Activity RNA Polymerase III Activity DNA Binding Protein Dimerization Activity
	Biological Process	Transcription From Mitochondrial Promoter Organelle Organization Mitochondrial Translation Positive Regulation Of Transcription, DNA-templated Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Regulation Of Gene Expression, Epigenetic Innate Immune Response Negative Regulation Of Gene Expression, Epigenetic
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination	RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Cytosolic sensors of pathogen-associated DNA Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Termination NoRC negatively regulates rRNA expression RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Chain Elongation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: COX6A2 OLIG1 POLR1D RARG TMEM51	15 interactors: CD3EAP CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C PXN
Entrez ID		6182	51082
HPRD ID		03849	17877
Ensembl ID		ENSG00000262814	ENSG00000186184
Uniprot IDs		P52815	Q9Y2S0
PDB IDs
Enriched GO Terms of Interacting Partners?		Growth Plate Cartilage Chondrocyte Growth Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy DNA-templated Transcription, Initiation Growth Plate Cartilage Chondrocyte Differentiation Retinal Pigment Epithelium Development Lacrimal Gland Development	Response To Organic Substance Cellular Response To Organic Substance Regulation Of Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Termination Of RNA Polymerase I Transcription Regulation Of Phosphorus Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transcription Elongation From RNA Polymerase I Promoter Response To Stimulus Transcription Initiation From RNA Polymerase I Promoter Cellular Metabolic Process Transcription, DNA-templated Transcription From RNA Polymerase I Promoter RNA Biosynthetic Process Regulation Of Protein Phosphorylation Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Determination Of Dorsal Identity Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Protein Phosphorylation Positive Regulation Of Transcription, DNA-templated Regulation Of Protein Kinase Activity Cellular Response To Stimulus Regulation Of Cellular Component Size DNA-templated Transcription, Termination Positive Regulation Of Neuron Death Negative Regulation Of Gene Expression, Epigenetic Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of Type I Interferon Production Positive Regulation Of Cytokine Production RNA Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Biosynthetic Process Response To Stress Gene Expression Nucleobase-containing Compound Metabolic Process
Tagcloud ?			anomalies cleft collins craniofacial daughters exome exon2 father favored feil hypoplasia inc kfs klippel l111p mandibular nonsynonymous palate pathogenetic periodicals predated rarity segmentation suggestive t332c tcs treacher wiley zygomatic
Tagcloud (Difference) ?			anomalies cleft collins craniofacial daughters exome exon2 father favored feil hypoplasia inc kfs klippel l111p mandibular nonsynonymous palate pathogenetic periodicals predated rarity segmentation suggestive t332c tcs treacher wiley zygomatic
Tagcloud (Intersection) ?