MRPL12 and OLIG1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		MRPL12	OLIG1
Description		mitochondrial ribosomal protein L12	oligodendrocyte transcription factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Chromatin Nucleus
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitochondrial Transcription Translation Mitochondrial Translation Positive Regulation Of DNA-templated Transcription	Sensory Organ Development Oligodendrocyte Development Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Axon Development
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial protein degradation Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Refractive error ( 32231278) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		25 interacting genes: CBX3 COX6A2 DRC8 EFEMP2 EXOC3L2 FBLN1 KRTAP10-1 MAPRE3 MICOS10-NBL1 MORF4L1 MORF4L2 NBL1 NTAQ1 NTM OLIG1 POLR1D PPP1R16A RARG SAT1 SEPTIN1 TMEM51 TRIM59 TXNDC9 UBC ZNF76	15 interacting genes: CACNA1A DOK4 DOK5 GRB2 HSH2D MRPL12 NCK1 NUMB PSMD14 PTPN6 RASA1 SH2D1A SH2D4A SHD STAT5A
Entrez ID		6182	116448
HPRD ID		03849	07333
Ensembl ID		ENSG00000262814	ENSG00000184221
Uniprot IDs		P52815	Q8TAK6
PDB IDs		6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7L08 7L20 7O9K 7O9M 7OG4 7PO2 7PO4 7QI4 7QI5 7QI6 8ANY 8OIR 8OIT
Enriched GO Terms of Interacting Partners?		Elastic Fiber Determination Of Dorsal Identity Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Morphogen Activity Negative Regulation Of Monocyte Chemotaxis Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction BMP Binding Negative Regulation Of Leukocyte Chemotaxis Negative Regulation Of Stem Cell Proliferation NuA4 Histone Acetyltransferase Complex	Phosphotyrosine Residue Binding Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Leukocyte Mediated Cytotoxicity Lymphocyte Activation Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Lymphocyte Mediated Immunity T Cell Activation Leukocyte Activation Leukocyte Mediated Immunity Enzyme-linked Receptor Protein Signaling Pathway Cell Activation Regulation Of T Cell Receptor Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Cell Killing Regulation Of Lymphocyte Mediated Immunity Protein-macromolecule Adaptor Activity Negative Regulation Of Immune System Process Positive Regulation Of T Cell Activation Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Actin Filament Polymerization Innate Immune Response Positive Regulation Of Lymphocyte Activation Regulation Of MAPK Cascade Positive Regulation Of Immune Response Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Leukocyte Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Immune Effector Process Regulation Of T Cell Activation Positive Regulation Of Cell Activation Ephrin Receptor Binding Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Symbiont Defense Response To Other Organism Regulation Of Cell Adhesion Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of B Cell Differentiation Vesicle Membrane Regulation Of Innate Immune Response Regulation Of T Cell Proliferation Cell-cell Junction T Cell Costimulation Negative Regulation Of Immune Response Positive Regulation Of Cell Adhesion
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