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POLR1D
Description
RNA polymerase I and III subunit D
Image
GO Annotations
Cellular Component
DNA-directed RNA Polymerase Complex
Nucleus
Nucleoplasm
RNA Polymerase III Complex
Nucleolus
RNA Polymerase I Complex
Cytosol
Nuclear DNA-directed RNA Polymerase Complex
Molecular Function
DNA Binding
DNA-directed RNA Polymerase Activity
Protein Binding
Protein Dimerization Activity
Biological Process
DNA-templated Transcription
Transcription Elongation By RNA Polymerase I
Transcription By RNA Polymerase III
Pathways
Cytosolic sensors of pathogen-associated DNA
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
Treacher Collins syndrome
GWAS
Body mass index (
26426971
)
Interacting Genes
15 interacting genes:
CDC25A
CEBPA
CRKL
DDIT3
DNAJB4
DNAJB6
E2F4
GRB2
HAX1
MAGEA11
MRPL12
NFKBIB
NR3C1
POLR1C
PXN
Entrez ID
51082
HPRD ID
17877
Ensembl ID
ENSG00000186184
Uniprot IDs
A0A087WTY1
P0DPB5
P0DPB6
PDB IDs
7A6H
7AE1
7AE3
7AEA
7AST
7D58
7D59
7DN3
7DU2
7FJI
7FJJ
7OB9
7OBA
7OBB
7VBA
7VBB
7VBC
8A43
8ITY
8IUE
8IUH
9FSO
9FSP
9FSQ
9FSR
9FSS
Enriched GO Terms of Interacting Partners
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CHOP-C/EBP Complex
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Transcription Regulator Complex
Regulation Of DNA-templated Transcription
Protein Domain Specific Binding
Regulation Of RNA Biosynthetic Process
Protein-folding Chaperone Binding
Transcription By RNA Polymerase I
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
RNA Polymerase II Transcription Regulator Complex
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of Gene Expression
ATPase Activator Activity
Nucleoplasm
Cytoplasm
Regulation Of Primary Metabolic Process
DNA-templated Transcription
Negative Regulation Of DNA-templated Transcription
Regulation Of Macromolecule Biosynthetic Process
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Cortex
Integrated Stress Response Signaling
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Response To Dexamethasone
Macrophage Differentiation
Positive Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Phosphotyrosine Residue Binding
Intrinsic Apoptotic Signaling Pathway In Response To Nitrosative Stress
Guanyl-nucleotide Exchange Factor Adaptor Activity
Nuclear Glucocorticoid Receptor Activity
Macromolecule Biosynthetic Process
Cytosol
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Xenobiotic Stimulus
Gland Development
Negative Regulation Of Biosynthetic Process
Response To Vitamin B2
C/EBP Complex
Helper T Cell Diapedesis
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