POLR1D and DNAJB4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		POLR1D	DNAJB4
Gene Name		polymerase (RNA) I polypeptide D, 16kDa	DnaJ (Hsp40) homolog, subfamily B, member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm DNA-directed RNA Polymerase III Complex DNA-directed RNA Polymerase I Complex Cytosol	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase I Activity RNA Polymerase III Activity DNA Binding Protein Dimerization Activity	Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Regulation Of Gene Expression, Epigenetic Innate Immune Response Negative Regulation Of Gene Expression, Epigenetic	Protein Folding Response To Unfolded Protein Response To Heat
Pathways		RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Cytosolic sensors of pathogen-associated DNA Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Termination NoRC negatively regulates rRNA expression RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Chain Elongation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CD3EAP CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C PXN	8 interactors: HSPA6 MDM2 OPRM1 PABPN1 POLR1D SMAD3 TBL1X TBPL2
Entrez ID		51082	11080
HPRD ID		17877	07486
Ensembl ID		ENSG00000186184
Uniprot IDs		Q9Y2S0	B4DNN2 Q9UDY4
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Cellular Response To Organic Substance Regulation Of Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Termination Of RNA Polymerase I Transcription Regulation Of Phosphorus Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transcription Elongation From RNA Polymerase I Promoter Response To Stimulus Transcription Initiation From RNA Polymerase I Promoter Cellular Metabolic Process Transcription, DNA-templated Transcription From RNA Polymerase I Promoter RNA Biosynthetic Process Regulation Of Protein Phosphorylation Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Determination Of Dorsal Identity Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Protein Phosphorylation Positive Regulation Of Transcription, DNA-templated Regulation Of Protein Kinase Activity Cellular Response To Stimulus Regulation Of Cellular Component Size DNA-templated Transcription, Termination Positive Regulation Of Neuron Death Negative Regulation Of Gene Expression, Epigenetic Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of Type I Interferon Production Positive Regulation Of Cytokine Production RNA Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Biosynthetic Process Response To Stress Gene Expression Nucleobase-containing Compound Metabolic Process	Modulation By Virus Of Host Morphology Or Physiology Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA-templated Transcription, Initiation Cellular Response To Alkaloid Response To Morphine Response To Cocaine Negative Regulation Of Cellular Metabolic Process Cellular Response To Organic Cyclic Compound Negative Regulation Of Transcription, DNA-templated DNA-templated Transcription, Termination Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Wnt Protein Secretion Positive Regulation Of Transforming Growth Factor Beta3 Production Cellular Response To UV-C Cellular Response To Vitamin B1 Transcription, DNA-templated Response To Ammonium Ion RNA Biosynthetic Process Immune Response Interaction With Host Positive Regulation Of Nucleocytoplasmic Transport Viral Process Modification By Virus Of Host MRNA Processing Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Response To Growth Factor Regulation Of Protein Transport Regulation Of Protein Stability Evasion Or Tolerance Of Host Defenses By Virus Response To Alkaloid Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Traversing Start Control Point Of Mitotic Cell Cycle Cellular Response To Morphine Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Extracellular Matrix Assembly Positive Regulation Of Appetite Response To Vitamin B1 Response To Ether Cellular Response To Isoquinoline Alkaloid Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Localization Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Primary MiRNA Processing
Tagcloud ?		anomalies cleft collins craniofacial daughters exome exon2 father favored feil hypoplasia inc kfs klippel l111p mandibular nonsynonymous palate pathogenetic periodicals predated rarity segmentation suggestive t332c tcs treacher wiley zygomatic	affinities anthanogene bag bag1 bag2 bag3 bcl2 chaperones cochaperones combinations combinatorial compete competed dnaja1 dnaja2 generate hierarchy hsp105 hsp70 hsp72 hspa1a mammals nef nefs permutations refolding stoichiometry unrelated
Tagcloud (Difference) ?		anomalies cleft collins craniofacial daughters exome exon2 father favored feil hypoplasia inc kfs klippel l111p mandibular nonsynonymous palate pathogenetic periodicals predated rarity segmentation suggestive t332c tcs treacher wiley zygomatic	affinities anthanogene bag bag1 bag2 bag3 bcl2 chaperones cochaperones combinations combinatorial compete competed dnaja1 dnaja2 generate hierarchy hsp105 hsp70 hsp72 hspa1a mammals nef nefs permutations refolding stoichiometry unrelated
Tagcloud (Intersection) ?