MRPL12 and COX6A2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MRPL12	COX6A2
Gene Name		mitochondrial ribosomal protein L12	cytochrome c oxidase subunit VIa polypeptide 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit	Mitochondrial Respiratory Chain Complex IV
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Cytochrome-c Oxidase Activity
	Biological Process	Transcription From Mitochondrial Promoter Organelle Organization Mitochondrial Translation Positive Regulation Of Transcription, DNA-templated Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Generation Of Precursor Metabolites And Energy Hydrogen Ion Transmembrane Transport
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: COX6A2 OLIG1 POLR1D RARG TMEM51	5 interactors: APP COL6A2 MRPL12 POT1 SNX21
Entrez ID		6182	1339
HPRD ID		03849	03598
Ensembl ID		ENSG00000262814	ENSG00000156885
Uniprot IDs		P52815	Q02221
PDB IDs
Enriched GO Terms of Interacting Partners?		Growth Plate Cartilage Chondrocyte Growth Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy DNA-templated Transcription, Initiation Growth Plate Cartilage Chondrocyte Differentiation Retinal Pigment Epithelium Development Lacrimal Gland Development	Positive Regulation Of DNA Strand Elongation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Telomere Formation Via Telomerase Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Positive Regulation Of Helicase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Neuron Remodeling Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Transcription From Mitochondrial Promoter Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Macromolecule Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Protein Heterotrimerization Axon Guidance Positive Regulation Of Cellular Biosynthetic Process Regulation Of Telomerase Activity Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly RNA-dependent DNA Replication Copper Ion Homeostasis Suckling Behavior Axonogenesis Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Telomere Maintenance Via Telomere Lengthening Neuron Projection Morphogenesis Mating Behavior Protein Trimerization Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation
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