MRPL12 and DRC8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRPL12	DRC8
Description		mitochondrial ribosomal protein L12	dynein regulatory complex subunit 8
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection Organelle Sperm Principal Piece
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Mitochondrial Transcription Translation Mitochondrial Translation Positive Regulation Of DNA-templated Transcription
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial protein degradation Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Refractive error ( 32231278) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		25 interacting genes: CBX3 COX6A2 DRC8 EFEMP2 EXOC3L2 FBLN1 KRTAP10-1 MAPRE3 MICOS10-NBL1 MORF4L1 MORF4L2 NBL1 NTAQ1 NTM OLIG1 POLR1D PPP1R16A RARG SAT1 SEPTIN1 TMEM51 TRIM59 TXNDC9 UBC ZNF76	5 interacting genes: ANTKMT MRPL12 TCL1B TNNI1 TNNI2
Entrez ID		6182	84288
HPRD ID		03849	14423
Ensembl ID		ENSG00000262814	ENSG00000203666
Uniprot IDs		P52815	Q5VUJ9
PDB IDs		6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7L08 7L20 7O9K 7O9M 7OG4 7PO2 7PO4 7QI4 7QI5 7QI6 8ANY 8OIR 8OIT	8J07
Enriched GO Terms of Interacting Partners?		Elastic Fiber Determination Of Dorsal Identity Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Morphogen Activity Negative Regulation Of Monocyte Chemotaxis Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction BMP Binding Negative Regulation Of Leukocyte Chemotaxis Negative Regulation Of Stem Cell Proliferation NuA4 Histone Acetyltransferase Complex	Troponin Complex Skeletal Muscle Contraction Cardiac Muscle Contraction Striated Muscle Contraction Troponin T Binding Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport Muscle Contraction Mitochondrial Transcription Transition Between Fast And Slow Fiber Muscle System Process Peptidyl-lysine Trimethylation Regulation Of Skeletal Muscle Adaptation Actin Binding Peptidyl-lysine Methylation Regulation Of ATP Biosynthetic Process Protein-lysine N-methyltransferase Activity
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