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RINT1 and RBL2
Number of citations of the paper that reports this interaction (PubMedID
16600870
)
0
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
HPRD
(in vitro, in vivo, two hybrid)
RINT1
RBL2
Description
RAD50 interactor 1
RB transcriptional corepressor like 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Dsl1/NZR Complex
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Chromosome
Nucleolus
Cytosol
Extracellular Exosome
Molecular Function
Protein Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
Protein Binding
Promoter-specific Chromatin Binding
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Mitotic G2 DNA Damage Checkpoint Signaling
Protein Transport
Vesicle-mediated Transport
Regulation Of ER To Golgi Vesicle-mediated Transport
Chromatin Organization
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Gene Expression
Cell Differentiation
Regulation Of Lipid Kinase Activity
Regulation Of Cell Cycle
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
COPI-dependent Golgi-to-ER retrograde traffic
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS
Appendicular lean mass (
33097823
)
Body fat mass (
28552196
)
Fasting insulin (
34059833
)
General cognitive ability (
29844566
)
Height (
28552196
)
Hip circumference adjusted for BMI (
34021172
)
Intelligence (MTAG) (
29326435
)
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Metabolite levels (
23823483
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
101 interacting genes:
AIRIM
ANKRD11
ARHGAP45
ARNT2
BFSP2
BLOC1S6
BNIP3L
C19orf44
C1orf35
CCDC120
CCDC121
CCDC146
CCDC187
CCDC57
CCDC88B
CCHCR1
CDR2L
CEP57L1
CSPP1
CWF19L2
DCTN2
DCX
DPF2
DRC4
EPC1
ESRRG
EXOC8
FAM107A
FAM110A
FAM124B
FAM161A
FAM161B
FAM81B
FAM90A1
FANCG
FCHSD2
GFI1B
GRAP2
HDAC4
HGS
INPP5J
JMY
KIAA1217
KRT1
LMO2
LSP1P3
LYSMD1
MBD3
MCM7
MISP
MYOZ3
NAB2
NFIL3
PCM1
PIK3R2
PIMREG
PRPF18
PRPF31
PSTPIP1
RAD50
RAMAC
RB1
RBL1
RBL2
RBM41
RIBC1
RNF39
RNF6
RSRC2
RTP5
SCNM1
SFR1
SGF29
SH2D4A
SMARCB1
SMARCE1
SNW1
SPTBN1
STRN
SUOX
TACO1
TEX9
TRIM69
TSEN54
TSHZ2
TSHZ3
TXLNA
USHBP1
UTP14C
VAV3
VPS37C
XPNPEP1
ZBTB16
ZC2HC1C
ZNF648
ZNF655
ZNF688
ZNF697
ZNF835
ZSCAN5B
ZW10
46 interacting genes:
BRCA1
BRF1
BRF2
BTG3
CCNA1
CCNA2
CCND1
CCND3
CCNE1
CDK2
CDK4
CDK6
CREG1
DCTN1
DGKZ
E2F4
E2F5
EZH2
GRAMD4
HBP1
HDAC1
ID2
KMT5C
LBX1
LDHC
LIN52
MCM7
MNDA
PCBD1
PHB1
PPP1R9B
PPP2CA
RAF1
RBBP8
RBBP9
RINT1
SKP2
SMARCA4
SNW1
SUV39H1
TAF1
TOP1
TP53BP1
UBTF
USP4
XBP1
Entrez ID
60561
5934
HPRD ID
15250
01576
Ensembl ID
ENSG00000135249
ENSG00000103479
Uniprot IDs
Q6NUQ1
Q08999
PDB IDs
4XI9
5C1D
Enriched GO Terms of Interacting Partners
?
Protein Binding
Cytoskeleton
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Lipid Kinase Activity
Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Microtubule Cytoskeleton Organization
Microtubule-based Process
Centrosome
SWI/SNF Complex
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
NBAF Complex
Nuclear Speck
Negative Regulation Of Cell Cycle Process
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of Double-strand Break Repair
Microtubule Anchoring
Centriole
Protein Localization To Centrosome
Regulation Of Sister Chromatid Segregation
Cytoskeleton Organization
Nucleoplasm
Regulation Of Nucleotide-excision Repair
Microtubule Binding
Cell Cycle G1/S Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Nucleoplasm
Regulation Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Process
Nucleus
Cell Cycle Phase Transition
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Cyclin-dependent Protein Kinase Holoenzyme Complex
Regulation Of RNA Metabolic Process
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Gene Expression
Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Regulation Of Primary Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Cellular Response To Stress
Negative Regulation Of Cell Cycle
Regulation Of Transcription By RNA Polymerase II
Regulation Of Metabolic Process
Regulation Of Cell Population Proliferation
Transcription Corepressor Activity
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
DNA Damage Response
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cyclin A2-CDK2 Complex
Cell Division
Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Cycle Phase Transition
Response To Stress
Transcription Regulator Complex
DNA Damage Checkpoint Signaling
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Nucleic Acid Metabolic Process
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Cycle Process
Transcription Preinitiation Complex Assembly
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Tagcloud (Intersection)
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