RINT1 and SNW1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RINT1	SNW1
Gene Name		RAD50 interactor 1	SNW domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Chromatin Nucleus Nucleoplasm Spliceosomal Complex Positive Transcription Elongation Factor Complex B Nuclear Matrix Catalytic Step 2 Spliceosome SMAD3-SMAD4 Protein Complex
	Molecular Function	Protein Binding	Transcription Coactivator Activity Transcription Corepressor Activity Notch Binding Protein Binding Nuclear Hormone Receptor Binding Vitamin D Receptor Binding Retinoic Acid Receptor Binding Poly(A) RNA Binding SMAD Binding
	Biological Process	Cell Cycle Protein Transport Golgi Vesicle Transport Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Gene Expression Viral Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation By Host Of Viral Transcription Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MRNA Splicing, Via Spliceosome Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Neurogenesis Positive Regulation Of Histone H3-K4 Methylation Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Retinoic Acid
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Notch-HLH transcription pathway Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway Pre-NOTCH Transcription and Translation Signaling by NOTCH1 Pre-NOTCH Expression and Processing Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS			Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
Protein-Protein Interactions		43 interactors: ARNT2 BNIP3L C1orf109 CCDC101 CCDC121 CCDC146 CEP57L1 CSPP1 CWF19L2 DCX EPC1 FAM107A FAM110A FAM124B FAM161A FAM81B FAM90A1 GFI1B HDAC4 LMO2 LSP1P3 PIK3R2 RAD50 RB1 RBL1 RBL2 RBM41 RIBC1 RSRC2 RTP5 SCNM1 SFR1 SH2D4A SMARCE1 SNW1 SPTBN1 STRN TXLNA VPS37C XPNPEP1 ZNF655 ZNF697 ZW10	58 interactors: ACTN2 ASCC2 CEP55 CIR1 CXorf56 DAXX EP300 GOLGA2 HDAC2 IKBKG IKZF1 JDP2 KRT40 LRP2BP LZTS2 MAGEA1 MAPK6 MEN1 MFAP1 MSL1 MTUS2 NCOR1 NCOR2 NHP2L1 NOTCH1 NOTCH3 NR0B1 NR0B2 PABPN1 PCBD2 PGR PPIL1 PRKAA2 RARA RB1 RBL1 RBL2 RBPJ RINT1 RXRA SART1 SIN3A SIRT1 SKI SMAD2 SMAD3 SMAD4 SRC TEX11 TFIP11 TNNT1 TOP1 TRAF1 TRIM15 TTC14 VAV2 VDR ZSCAN1
Entrez ID		60561	22938
HPRD ID		15250	04340
Ensembl ID		ENSG00000135249	ENSG00000100603
Uniprot IDs		Q6NUQ1	G3V3A4 Q13573
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Modification Regulation Of Lipid Kinase Activity Chromatin Organization Protein Localization To Chromosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Organelle Organization RNA Metabolic Process Protein Localization To Chromosome, Centromeric Region Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of Histone H3-K4 Methylation Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Lipid Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Mitotic Metaphase Plate Congression Viral Process Positive Regulation Of Cellular Biosynthetic Process Metaphase Plate Congression Regulation Of Cell Cycle Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Establishment Of Chromosome Localization Microtubule Anchoring Chromatin Remodeling Regulation Of Histone Methylation Regulation Of Chromosome Organization Mitotic Cell Cycle Positive Regulation Of Vitamin D Receptor Signaling Pathway	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Organic Substance Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization Chromatin Modification Organ Development Regulation Of Signal Transduction Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Signaling Regulation Of Binding Response To Transforming Growth Factor Beta Positive Regulation Of Metabolic Process Cell Cycle Chromosome Organization Negative Regulation Of Cell Differentiation
Tagcloud ?		apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde sec39 summarize tethering tip20 trafficking transport vesicle zw10	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Difference) ?		apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde sec39 summarize tethering tip20 trafficking transport vesicle zw10	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Intersection) ?