RINT1 and XPNPEP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		RINT1	XPNPEP1
Gene Name		RAD50 interactor 1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Aminopeptidase Activity Manganese Ion Binding Protein Homodimerization Activity Metalloaminopeptidase Activity
	Biological Process	Cell Cycle Protein Transport Golgi Vesicle Transport Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint	Proteolysis Bradykinin Catabolic Process
Pathways
Drugs
Diseases
GWAS			Biliary atresia ( 20460270)
Protein-Protein Interactions		43 interactors: ARNT2 BNIP3L C1orf109 CCDC101 CCDC121 CCDC146 CEP57L1 CSPP1 CWF19L2 DCX EPC1 FAM107A FAM110A FAM124B FAM161A FAM81B FAM90A1 GFI1B HDAC4 LMO2 LSP1P3 PIK3R2 RAD50 RB1 RBL1 RBL2 RBM41 RIBC1 RSRC2 RTP5 SCNM1 SFR1 SH2D4A SMARCE1 SNW1 SPTBN1 STRN TXLNA VPS37C XPNPEP1 ZNF655 ZNF697 ZW10	8 interactors: DISC1 GSK3B MAPK9 NUDT3 POLA2 RINT1 UBC UBE2D3
Entrez ID		60561	7511
HPRD ID		15250	03899
Ensembl ID		ENSG00000135249	ENSG00000108039
Uniprot IDs		Q6NUQ1	G8JLB2 Q9NQW7
PDB IDs			3CTZ
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Modification Regulation Of Lipid Kinase Activity Chromatin Organization Protein Localization To Chromosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Organelle Organization RNA Metabolic Process Protein Localization To Chromosome, Centromeric Region Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of Histone H3-K4 Methylation Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Lipid Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Mitotic Metaphase Plate Congression Viral Process Positive Regulation Of Cellular Biosynthetic Process Metaphase Plate Congression Regulation Of Cell Cycle Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Establishment Of Chromosome Localization Microtubule Anchoring Chromatin Remodeling Regulation Of Histone Methylation Regulation Of Chromosome Organization Mitotic Cell Cycle Positive Regulation Of Vitamin D Receptor Signaling Pathway	TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Proteolysis Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Innate Immune Response Cellular Localization Response To Growth Factor Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Protein Ubiquitination Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Fc-epsilon Receptor Signaling Pathway Intracellular Transport Regulation Of Innate Immune Response Fc Receptor Signaling Pathway Innate Immune Response Negative Regulation Of Type I Interferon Production Regulation Of Wnt Signaling Pathway Regulation Of Immune Response Positive Regulation Of Protein Modification Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of DNA-templated Transcription In Response To Stress Protein Localization Apoptotic Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Apoptotic Process Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Glycogen Metabolic Process Establishment Of Localization In Cell Programmed Cell Death Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Catabolic Process Cell Death Death MyD88-dependent Toll-like Receptor Signaling Pathway Response To Abiotic Stimulus
Tagcloud ?		apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde sec39 summarize tethering tip20 trafficking transport vesicle zw10	aminopeptidase app app1 apps associate biologically causal cleave cytosolic deficiency deficient excretion imino isoforms knocking lethality link mammals microcephaly modest oligopeptide penultimate peptides peptiduria proline ps residue retardation
Tagcloud (Difference) ?		apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde sec39 summarize tethering tip20 trafficking transport vesicle zw10	aminopeptidase app app1 apps associate biologically causal cleave cytosolic deficiency deficient excretion imino isoforms knocking lethality link mammals microcephaly modest oligopeptide penultimate peptides peptiduria proline ps residue retardation
Tagcloud (Intersection) ?