RINT1 and JMY

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RINT1	JMY
Description		RAD50 interactor 1	junction mediating and regulatory protein, p53 cofactor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Dsl1/NZR Complex	Autophagosome Membrane Nucleus Nucleoplasm Cytoplasm Cytoskeleton Endomembrane System Membrane Cell Leading Edge Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Transcription Coactivator Activity Actin Binding Protein Binding Microtubule Binding Arp2/3 Complex Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Mitotic G2 DNA Damage Checkpoint Signaling Protein Transport Vesicle-mediated Transport Regulation Of ER To Golgi Vesicle-mediated Transport	DNA Repair Regulation Of Transcription By RNA Polymerase II DNA Damage Response Cellular Response To Starvation Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription 'de Novo' Actin Filament Nucleation Actin Polymerization-dependent Cell Motility Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways		COPI-dependent Golgi-to-ER retrograde traffic	Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS			Blood and toenail selenium levels ( 25343990) Cryptococcosis in HIV infection ( 33269293) Platelet distribution width ( 32888494) Toenail selenium levels ( 25343990)
Interacting Genes		101 interacting genes: AIRIM ANKRD11 ARHGAP45 ARNT2 BFSP2 BLOC1S6 BNIP3L C19orf44 C1orf35 CCDC120 CCDC121 CCDC146 CCDC187 CCDC57 CCDC88B CCHCR1 CDR2L CEP57L1 CSPP1 CWF19L2 DCTN2 DCX DPF2 DRC4 EPC1 ESRRG EXOC8 FAM107A FAM110A FAM124B FAM161A FAM161B FAM81B FAM90A1 FANCG FCHSD2 GFI1B GRAP2 HDAC4 HGS INPP5J JMY KIAA1217 KRT1 LMO2 LSP1P3 LYSMD1 MBD3 MCM7 MISP MYOZ3 NAB2 NFIL3 PCM1 PIK3R2 PIMREG PRPF18 PRPF31 PSTPIP1 RAD50 RAMAC RB1 RBL1 RBL2 RBM41 RIBC1 RNF39 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN SUOX TACO1 TEX9 TRIM69 TSEN54 TSHZ2 TSHZ3 TXLNA USHBP1 UTP14C VAV3 VPS37C XPNPEP1 ZBTB16 ZC2HC1C ZNF648 ZNF655 ZNF688 ZNF697 ZNF835 ZSCAN5B ZW10	8 interacting genes: CCDC136 EP300 GOLGA6L9 MDM2 MTUS2 RBM48 RINT1 TTC5
Entrez ID		60561	133746
HPRD ID		15250	05045
Ensembl ID		ENSG00000135249	ENSG00000152409
Uniprot IDs		Q6NUQ1	Q8N9B5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoskeleton Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition Microtubule Cytoskeleton Organization Microtubule-based Process Centrosome SWI/SNF Complex Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition NBAF Complex Nuclear Speck Negative Regulation Of Cell Cycle Process Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Double-strand Break Repair Microtubule Anchoring Centriole Protein Localization To Centrosome Regulation Of Sister Chromatid Segregation Cytoskeleton Organization Nucleoplasm Regulation Of Nucleotide-excision Repair Microtubule Binding	Response To Estrogen Positive Regulation Of Establishment Of Protein Localization Peptidyl-lysine Propionylation DNA Damage Response Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Protein Destabilization Histone Butyryltransferase Activity Positive Regulation Of Nucleocytoplasmic Transport Cellular Response To Nutrient Levels Histone Crotonyltransferase Activity Regulation Of Intracellular Transport Positive Regulation Of Protein Transport Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Response To Formaldehyde Cellular Response To Vitamin B1 P53 Binding Histone H2B Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Cellular Response To Light Stimulus Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Cellular Response To UV Histone H3K18 Acetyltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Thigmotaxis Histone H3K27 Acetyltransferase Activity Regulation Of Protein Transport Positive Regulation Of Intracellular Protein Transport Peptide Crotonyltransferase Activity Positive Regulation Of Protein Localization Signal Transduction By P53 Class Mediator Peptide Lactyltransferase (CoA-dependent) Activity Proteinase-activated Receptor Activity Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Response To Vitamin B1 Response To Water-immersion Restraint Stress Cellular Response To Actinomycin D Dsl1/NZR Complex Modulation Of Process Of Another Organism Response To Nutrient Levels
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