ELAC2 and ASCC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ELAC2	ASCC2
Gene Name		elaC ribonuclease Z 2	activating signal cointegrator 1 complex subunit 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Endonuclease Activity Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ASCC2 CTBP1 CTBP2 CUX1 GOLM1 NDUFA7 RING1 SMAD2	38 interactors: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT JUN KDM1A LPL MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RELA RNF11 RPA1 RPLP1 SNRPB SNW1 SRF TBC1D17 TRIP4 URM1
Entrez ID		60528	84164
HPRD ID		05641	16515
Ensembl ID		ENSG00000006744	ENSG00000100325
Uniprot IDs		G5E9D5 Q9BQ52	Q9H1I8
PDB IDs			2DI0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process White Fat Cell Differentiation Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Viral Genome Replication Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Fat Cell Differentiation Regulation Of RNA Metabolic Process Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Negative Regulation Of Cell Proliferation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Viral Life Cycle Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Primary MiRNA Processing Positive Regulation Of Chromatin Binding Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Activin Receptor Signaling Pathway Lung Development Anterior/posterior Pattern Specification Respiratory Tube Development Negative Regulation Of Histone H4 Acetylation Regulation Of Binding	Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Myeloid Leukocyte Differentiation RNA Metabolic Process Nitrogen Compound Metabolic Process Myeloid Cell Differentiation Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation By Host Of Viral Transcription Leukocyte Differentiation RNA Biosynthetic Process Metabolic Process Response To Abiotic Stimulus Mitochondrion Organization Hemopoiesis Monocyte Differentiation Transcription, DNA-templated Telomere Maintenance Via Semi-conservative Replication Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Platelet Formation Protein Tetramerization Response To Radiation Platelet Morphogenesis Immune System Development Macromolecule Biosynthetic Process Telomere Maintenance Via Recombination Regulation Of Histone H3-K4 Methylation Nuclear DNA Replication Positive Regulation Of Transcription, DNA-templated Response To CAMP Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Response To Drug DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Response To Stress Gene Expression Blood Vessel Endothelial Cell Migration Interaction With Symbiont Learning Membrane Protein Proteolysis Aging Regulation Of Cell Proliferation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organophosphorus Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		abundant biogenesis cointroducing constitute created discover discovered endonuclease g2 ligation mature micrornas mirnas northern oligoribonucleotide precise progressively retained rnas sequenced splinted tga throughput tightly trf trfs trna trnas ultra
Tagcloud (Difference) ?		abundant biogenesis cointroducing constitute created discover discovered endonuclease g2 ligation mature micrornas mirnas northern oligoribonucleotide precise progressively retained rnas sequenced splinted tga throughput tightly trf trfs trna trnas ultra
Tagcloud (Intersection) ?