ELAC2 and NDUFA7

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ELAC2	NDUFA7
Gene Name		elaC ribonuclease Z 2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	Endonuclease Activity Poly(A) RNA Binding Metal Ion Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic	Mitochondrial Electron Transport, NADH To Ubiquinone Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ASCC2 CTBP1 CTBP2 CUX1 GOLM1 NDUFA7 RING1 SMAD2	5 interactors: ELAC2 MDFI PRKAB1 STARD9 UPF2
Entrez ID		60528	4701
HPRD ID		05641	11885
Ensembl ID		ENSG00000006744	ENSG00000267855
Uniprot IDs		G5E9D5 Q9BQ52	O95182
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process White Fat Cell Differentiation Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Viral Genome Replication Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Fat Cell Differentiation Regulation Of RNA Metabolic Process Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Negative Regulation Of Cell Proliferation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Viral Life Cycle Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Primary MiRNA Processing Positive Regulation Of Chromatin Binding Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Activin Receptor Signaling Pathway Lung Development Anterior/posterior Pattern Specification Respiratory Tube Development Negative Regulation Of Histone H4 Acetylation Regulation Of Binding	Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic TRNA 3'-trailer Cleavage Mitochondrial RNA 3'-end Processing TRNA 3'-end Processing
Tagcloud ?		abundant biogenesis cointroducing constitute created discover discovered endonuclease g2 ligation mature micrornas mirnas northern oligoribonucleotide precise progressively retained rnas sequenced splinted tga throughput tightly trf trfs trna trnas ultra
Tagcloud (Difference) ?		abundant biogenesis cointroducing constitute created discover discovered endonuclease g2 ligation mature micrornas mirnas northern oligoribonucleotide precise progressively retained rnas sequenced splinted tga throughput tightly trf trfs trna trnas ultra
Tagcloud (Intersection) ?