NIF3L1 and KLRC2

		NIF3L1	KLRC2
Description		NGG1 interacting factor 3 like 1	killer cell lectin like receptor C2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Plasma Membrane External Side Of Plasma Membrane Membrane Receptor Complex
	Molecular Function	Protein Binding Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding MHC Class Ib Receptor Activity Activating MHC Class Ib Receptor Activity Protein Antigen Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Neuron Differentiation Positive Regulation Of DNA-templated Transcription	Stimulatory C-type Lectin Receptor Signaling Pathway Natural Killer Cell Mediated Immunity Adaptive Immune Response Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Defense Response Signal Transduction Regulation Of Natural Killer Cell Activation Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Degranulation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Pathways			DAP12 interactions DAP12 signaling DAP12 signaling
Drugs
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Composite immunoglobulin trait (IgA/IgG) ( 28628107) Liver enzyme levels (alanine transaminase) ( 33972514) Lymphocyte count ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 27863252 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		93 interacting genes: ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1	3 interacting genes: FBP1 HLA-E KLRD1
Entrez ID		60491	3822
HPRD ID		10424	04202
Ensembl ID		ENSG00000196290	ENSG00000205809
Uniprot IDs		Q9GZT8	P26717
PDB IDs			2L35
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoplasm Protein Binding Cytosol Protein Complex Oligomerization Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Ethanol Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Nucleoside Phosphate Metabolic Process Phosphate-containing Compound Metabolic Process Sulfation Pyrimidine Nucleotide Metabolic Process Polyamine Catabolic Process Nucleus Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Activation Regulation Of T Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Positive Regulation Of Antibody-dependent Cellular Cytotoxicity Negative Regulation Of Innate Immune Response Regulation Of Leukocyte Mediated Cytotoxicity Phosphoric Ester Hydrolase Activity Cellular Response To Raffinose Fructose 1,6-bisphosphate 1-phosphatase Activity Regulation Of T Cell Mediated Immunity Positive Regulation Of Lymphocyte Mediated Immunity Lymphocyte Mediated Immunity MHC Class Ib Protein Complex Positive Regulation Of TRAIL Production HLA-E Specific Inhibitory MHC Class Ib Receptor Activity MHC Class Ib Protein Binding, Via Antigen Binding Groove Leukocyte Mediated Immunity Cellular Hypotonic Salinity Response Positive Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Regulation Of TRAIL Production Natural Killer Cell Tolerance Induction Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class Ib Positive Regulation Of Type IIa Hypersensitivity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Lymphocyte Mediated Immunity Cellular Hyperosmotic Salinity Response Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Negative Regulation Of Immune Response Regulation Of Adaptive Immune Response Hyperosmotic Salinity Response Cellular Response To Magnesium Ion Protection From Natural Killer Cell Mediated Cytotoxicity Monosaccharide Binding Positive Regulation Of Hypersensitivity MHC Class I Protein Complex Binding Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Beta-2-microglobulin Binding Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation Natural Killer Cell Lectin-like Receptor Binding Positive Regulation Of Immune Effector Process MHC Class I Protein Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?