PPCDC and SREK1IP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PPCDC	SREK1IP1
Gene Name		phosphopantothenoylcysteine decarboxylase	SREK1-interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Phosphopantothenoylcysteine Decarboxylase Activity	Nucleic Acid Binding Zinc Ion Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process Pantothenate Metabolic Process Small Molecule Metabolic Process	MRNA Processing RNA Splicing
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707)
Protein-Protein Interactions		8 interactors: CENPT DBI FOXR1 PPIG SREK1IP1 TXN2 WDYHV1 ZNF232	8 interactors: HSD17B14 NME1 PPCDC RBM39 RP9P SDCBP SDCBP2 STAC3
Entrez ID		60490	285672
HPRD ID		14377	08210
Ensembl ID		ENSG00000138621	ENSG00000153006
Uniprot IDs		H3BRQ0 Q96CD2	Q8N9Q2
PDB IDs		1QZU
Enriched GO Terms of Interacting Partners?			Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Purine Nucleoside Metabolic Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Substrate-dependent Cell Migration, Cell Extension Pantothenate Metabolic Process Ribose Phosphate Metabolic Process Nucleobase-containing Small Molecule Interconversion Coenzyme A Biosynthetic Process Skeletal Muscle Fiber Development Steroid Catabolic Process
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