PPCDC and DBI

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PPCDC	DBI
Gene Name		phosphopantothenoylcysteine decarboxylase	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
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Gene Ontology Annotations	Cellular Component	Cytosol	Mitochondrion Endoplasmic Reticulum Golgi Apparatus Extracellular Vesicular Exosome Perinuclear Endoplasmic Reticulum
	Molecular Function	Phosphopantothenoylcysteine Decarboxylase Activity	Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Protein Dimerization Activity
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process Pantothenate Metabolic Process Small Molecule Metabolic Process	Behavioral Fear Response Hair Follicle Development Triglyceride Metabolic Process Transport Learning Or Memory Protein Palmitoylation Lateral Ventricle Development Phosphatidylcholine Acyl-chain Remodeling Long-term Synaptic Potentiation
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: CENPT DBI FOXR1 PPIG SREK1IP1 TXN2 WDYHV1 ZNF232	10 interactors: DUSP23 GSK3B MAP1LC3B NIPSNAP1 NSFL1C PPCDC RAD23A RAD23B TSPO UBXN2A
Entrez ID		60490	1622
HPRD ID		14377	08832
Ensembl ID		ENSG00000138621	ENSG00000155368
Uniprot IDs		H3BRQ0 Q96CD2	B8ZWD1 P07108
PDB IDs		1QZU	2CB8 2FJ9
Enriched GO Terms of Interacting Partners?			Cellular Response To Stress Autophagic Vacuole Assembly Macroautophagy Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Vacuole Organization Nuclear Envelope Reassembly Regulation Of Protein Catabolic Process Membrane Fusion Response To Nutrient Levels Cellular Response To Starvation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Extracellular Stimulus Ubiquitin-dependent Protein Catabolic Process Autophagy Modification-dependent Protein Catabolic Process Cellular Response To Nutrient Levels Response To Starvation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Protein Catabolic Process Cellular Response To Extracellular Stimulus Response To Stress Cellular Macromolecule Catabolic Process Nuclear Envelope Organization Catabolic Process Response To External Stimulus Golgi Organization Nucleotide-excision Repair Negative Regulation Of Type B Pancreatic Cell Development Nucleotide-excision Repair, DNA Damage Recognition Superior Temporal Gyrus Development Organelle Assembly Nucleus Organization Re-entry Into Mitotic Cell Cycle Response To Vitamin B1 Negative Regulation Of Neuron Maturation Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Necrotic Cell Death Cellular Response To Interleukin-3 Regulation Of Proteolysis Proteolysis Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Neuron Maturation Cellular Metabolic Process Protein Localization To Microtubule Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Dendrite Morphogenesis
Tagcloud ?			abolishes availability bear box cdna cloned contains dead diminishes display fibroblast identity kb message mitogenic nontransforming notch overexpressed place recognize repeats solely take terminally terminus transcript transform transforming truncated
Tagcloud (Difference) ?			abolishes availability bear box cdna cloned contains dead diminishes display fibroblast identity kb message mitogenic nontransforming notch overexpressed place recognize repeats solely take terminally terminus transcript transform transforming truncated
Tagcloud (Intersection) ?