PPCDC and DBI

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PPCDC	DBI
Description		phosphopantothenoylcysteine decarboxylase	diazepam binding inhibitor, acyl-CoA binding protein
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GO Annotations	Cellular Component	Cytosol Phosphopantothenoylcysteine Decarboxylase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Protein-lipid Complex Extracellular Exosome Perinuclear Endoplasmic Reticulum
	Molecular Function	Catalytic Activity Phosphopantothenoylcysteine Decarboxylase Activity Protein Binding FMN Binding Lyase Activity Carboxy-lyase Activity Identical Protein Binding	Fatty-acyl-CoA Binding Protein Binding Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Identical Protein Binding
	Biological Process	Coenzyme A Biosynthetic Process	Fatty Acid Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Negative Regulation Of Protein Lipidation Positive Regulation Of Phospholipid Transport
Pathways		Coenzyme A biosynthesis	Mitochondrial Fatty Acid Beta-Oxidation
Drugs		Flavin mononucleotide Pantothenoylaminoethenethiol	Coenzyme A Hexadecanal
Diseases
GWAS		Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Apolipoprotein A1 levels ( 32203549) Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Coffee consumption (cups per day) ( 31837886) Heel bone mineral density ( 30598549) Lymphocyte count ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Multisite chronic pain ( 33830993) Neutrophil count ( 32888494) Platelet count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic lupus erythematosus ( 26502338) White blood cell count ( 32888494)	Obesity-related traits ( 23251661)
Interacting Genes		13 interacting genes: CENPT DBI DDIT4L FOXR1 NAA80 NTAQ1 PLEKHF2 PPIG PSMA1 SREK1IP1 TXN2 UBE2I ZNF232	14 interacting genes: CYSLTR2 DDIT4L DUSP23 GSK3B LAMTOR5 MAP1LC3B NIPSNAP1 NSFL1C PFDN2 PPCDC RAD23A RAD23B TSPO UBXN2A
Entrez ID		60490	1622
HPRD ID		14377	08832
Ensembl ID		ENSG00000138621	ENSG00000155368
Uniprot IDs		H3BQB0 H3BRQ0 H3BSE3 H3BU63 Q96CD2	A0A024RAF2 B8ZWD1 B8ZWD8 P07108
PDB IDs		1QZU	2CB8 2FJ9
Enriched GO Terms of Interacting Partners?			Ubiquitin Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Protein Localization To Centrosome Proteasomal Protein Catabolic Process Autophagosome Assembly Autophagosome Organization Protein Catabolic Process Proteasome Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Organelle Assembly Nuclear Membrane Reassembly Regulation Of Proteolysis Cytosol Regulation Of Ubiquitin-dependent Protein Catabolic Process Catabolic Process Vacuole Organization Polyubiquitin Modification-dependent Protein Binding Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Corticosterone Secretion Regulation Of Protein Metabolic Process Regulation Of Microtubule Anchoring At Centrosome Nuclear Membrane Organization Cysteinyl Leukotriene Receptor Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Nucleotide-excision Repair Regulation Of Post-translational Protein Modification Macromolecule Catabolic Process Mitophagy Membrane Assembly Negative Regulation Of Protein Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Proteasome Complex Damaged DNA Binding Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Autophagy Of Mitochondrion VCP-NSFL1C Complex Negative Regulation Of Protein Localization To Centrosome Proteolysis Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
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