PPCDC and ZNF232

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PPCDC	ZNF232
Gene Name		phosphopantothenoylcysteine decarboxylase	zinc finger protein 232
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus
	Molecular Function	Phosphopantothenoylcysteine Decarboxylase Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process Pantothenate Metabolic Process Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707)
Protein-Protein Interactions		8 interactors: CENPT DBI FOXR1 PPIG SREK1IP1 TXN2 WDYHV1 ZNF232	6 interactors: EMD MTUS2 NR2E3 PPCDC YY1 ZNF446
Entrez ID		60490	7775
HPRD ID		14377	15755
Ensembl ID		ENSG00000138621	ENSG00000167840
Uniprot IDs		H3BRQ0 Q96CD2	I3L4J6 Q9UNY5
PDB IDs		1QZU
Enriched GO Terms of Interacting Partners?			Response To Prostaglandin F Eye Morphogenesis Transcription From RNA Polymerase II Promoter Positive Regulation Of Rhodopsin Gene Expression Regulation Of Rhodopsin Gene Expression Mitotic Nuclear Envelope Reassembly Response To Light Stimulus Response To UV-C Negative Regulation Of Catenin Import Into Nucleus Camera-type Eye Development Nuclear Envelope Reassembly Pantothenate Metabolic Process Eye Development Positive Regulation Of Protein Export From Nucleus Response To Radiation Coenzyme A Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Catenin Import Into Nucleus Coenzyme A Metabolic Process Nucleobase-containing Compound Metabolic Process Sensory Organ Development Regulation Of Protein Export From Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Mitotic Nuclear Envelope Disassembly Negative Regulation Of Cell Proliferation Negative Regulation Of Fibroblast Proliferation Transcription, DNA-templated Eye Photoreceptor Cell Development Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nuclear Envelope Disassembly Photoreceptor Cell Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Photoreceptor Cell Differentiation Response To Organic Substance
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