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PPCDC and PPIG
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PPCDC
PPIG
Gene Name
phosphopantothenoylcysteine decarboxylase
peptidylprolyl isomerase G (cyclophilin G)
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
Nuclear Speck
Molecular Function
Phosphopantothenoylcysteine Decarboxylase Activity
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
Cyclosporin A Binding
Poly(A) RNA Binding
Biological Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Coenzyme Biosynthetic Process
Coenzyme A Biosynthetic Process
Pantothenate Metabolic Process
Small Molecule Metabolic Process
Protein Peptidyl-prolyl Isomerization
Protein Folding
RNA Splicing
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Vitamin B5 (pantothenate) metabolism
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMAA causes methylmalonic aciduria type cblA
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Coenzyme A biosynthesis
Defective TCN2 causes hereditary megaloblastic anemia
Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Blood trace element (Zn levels) (
23720494
)
Caffeine consumption (
21490707
)
Protein-Protein Interactions
8 interactors:
CENPT
DBI
FOXR1
PPIG
SREK1IP1
TXN2
WDYHV1
ZNF232
25 interactors:
BEND7
CACNA1A
CEP70
CLK1
DAB1
DACH1
FHL3
KCTD6
LGALS3
NKAP
PCBP1
PNMA2
PNN
POLR2A
PPCDC
PRPF38A
PRPF40A
RBM39
SLU7
SMN2
SP1
TFCP2
THAP1
YWHAG
ZCCHC10
Entrez ID
60490
9360
HPRD ID
14377
12083
Ensembl ID
ENSG00000138621
ENSG00000138398
Uniprot IDs
H3BRQ0
Q96CD2
Q13427
PDB IDs
1QZU
2GW2
2WFI
2WFJ
Enriched GO Terms of Interacting Partners
?
RNA Splicing
MRNA Processing
MRNA Metabolic Process
RNA Processing
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Transcription, DNA-templated
Positive Regulation Of Viral Transcription
Adult Walking Behavior
Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
Cerebellar Molecular Layer Development
Negative Regulation Of Immunological Synapse Formation
Sequestering Of Nodal From Receptor Via Nodal Binding
Cerebellum Morphogenesis
RNA Biosynthetic Process
Hindbrain Morphogenesis
DNA-templated Transcription, Initiation
Ventral Spinal Cord Development
Spliceosomal Complex Assembly
Vestibular Nucleus Development
Negative Regulation Of Nodal Signaling Pathway
Cerebellum Structural Organization
Transcription, RNA-templated
Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Regulation Of Viral Transcription
Cellular Metabolic Process
Positive Regulation Of Viral Process
Cerebellum Maturation
Lateral Motor Column Neuron Migration
RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Musculoskeletal Movement, Spinal Reflex Action
Positive Regulation Of Mononuclear Cell Migration
Spinal Cord Motor Neuron Migration
Mononuclear Cell Migration
Gamma-aminobutyric Acid Secretion
Regulation Of RNA Splicing
Cell Proliferation
Radial Glia Guided Migration Of Purkinje Cell
MRNA 3'-splice Site Recognition
Negative Regulation Of Cell Proliferation Involved In Contact Inhibition
Regulation Of Acetylcholine Secretion, Neurotransmission
Spinal Cord Development
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Tagcloud (Intersection)
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