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RAN and TNPO1
Number of citations of the paper that reports this interaction (PubMedID
27114554
)
46
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
RAN
TNPO1
Description
RAN, member RAS oncogene family
transportin 1
Image
GO Annotations
Cellular Component
Chromatin
Male Germ Cell Nucleus
Manchette
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Nucleolus
Cytoplasm
Centriole
Cytosol
Membrane
Midbody
Protein-containing Complex
Sperm Flagellum
Melanosome
RNA Nuclear Export Complex
Recycling Endosome
Extracellular Exosome
Flemming Body
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Cilium
Nuclear Lumen
Extracellular Exosome
Molecular Function
Nucleotide Binding
Magnesium Ion Binding
Chromatin Binding
RNA Binding
GTPase Activity
G Protein Activity
Nuclear Export Signal Receptor Activity
Protein Binding
GTP Binding
Hydrolase Activity
GDP Binding
Protein Domain Specific Binding
Protein-containing Complex Binding
Cadherin Binding
Dynein Intermediate Chain Binding
Metal Ion Binding
Protein Heterodimerization Activity
Importin-alpha Family Protein Binding
Pre-miRNA Binding
RNA Binding
Protein Binding
Nuclear Localization Sequence Binding
Small GTPase Binding
Nuclear Import Signal Receptor Activity
Biological Process
Ribosomal Subunit Export From Nucleus
Ribosomal Large Subunit Export From Nucleus
Ribosomal Small Subunit Export From Nucleus
Mitotic Sister Chromatid Segregation
Mitotic Cell Cycle
Glycolytic Process
DNA Metabolic Process
Protein Import Into Nucleus
Protein Export From Nucleus
Nucleocytoplasmic Transport
Mitotic Spindle Organization
Spermatid Development
Intracellular Protein Localization
Protein Transport
Viral Process
Hippocampus Development
Actin Cytoskeleton Organization
Protein-containing Complex Localization
Pre-miRNA Export From Nucleus
Positive Regulation Of Protein Import Into Nucleus
GTP Metabolic Process
Cell Division
SnRNA Import Into Nucleus
Cellular Response To Mineralocorticoid Stimulus
Protein Localization To Nucleolus
Protein Import Into Nucleus
Intracellular Protein Transport
Protein Transport
Pathways
Rev-mediated nuclear export of HIV RNA
Regulation of cholesterol biosynthesis by SREBP (SREBF)
NEP/NS2 Interacts with the Cellular Export Machinery
Nuclear import of Rev protein
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
tRNA processing in the nucleus
Postmitotic nuclear pore complex (NPC) reformation
Postmitotic nuclear pore complex (NPC) reformation
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
Intraflagellar transport
Postmitotic nuclear pore complex (NPC) reformation
Drugs
Guanosine-5'-Diphosphate
Diseases
GWAS
Chronic obstructive pulmonary disease (
30804561
)
Factor VIII levels (
30586737
)
Height (
31562340
)
Hemoglobin (
32888494
)
Liver enzyme levels (gamma-glutamyl transferase) (
33972514
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular hemoglobin concentration (
27863252
29403010
32888494
)
Mean platelet volume (
27863252
32888494
)
Medication use (thyroid preparations) (
31015401
)
Platelet count (
32888494
27863252
)
Plateletcrit (
32888494
)
Red cell distribution width (
28957414
32888494
)
Serum albumin levels (
29403010
)
vWF levels (
30586737
)
Interacting Genes
62 interacting genes:
ABL1
ADRB2
AR
ASAP2
BCAR1
BIRC5
BMPR1B
CEP126
CSE1L
DUX4
EP300
FNDC3B
FOXP1
GADD45G
GIT1
IPO11
IPO13
IPO4
IPO5
IPO7
IPO8
IPO9
KPNB1
MBP
MSL1
NEK9
NR3C1
NSMF
NUP153
NUP50
NUTF2
NXF1
NXT1
PAK4
PARP10
PTMA
RANBP1
RANBP10
RANBP2
RANBP3
RANBP9
RANGAP1
RANGRF
RCC1
RGPD5
RPL7
SMAD1
SMAD2
SMARCB1
SMURF2
SPAG8
SSRP1
SUMO2
TGFBR1
TNPO1
VRK2
VRK3
XPO1
XPO4
XPO5
XPO7
XPOT
19 interacting genes:
ELAVL1
H2BC21
H3-4
HNRNPA1
HNRNPD
NUP153
NUP214
NUP98
NXF1
PABPN1
RAN
RANBP2
RGPD5
RNF10
RPL23A
RPL5
RPS7
SRP19
ULK2
Entrez ID
5901
3842
HPRD ID
03109
04210
Ensembl ID
ENSG00000132341
ENSG00000083312
Uniprot IDs
B4DV51
P62826
A0A7P0TBF0
Q92973
PDB IDs
1I2M
1IBR
1K5D
1K5G
1QBK
1RRP
2MMC
2MMG
2N1B
3CH5
3EA5
3GJ0
3GJ3
3GJ4
3GJ5
3GJ6
3GJ7
3GJ8
3GJX
3NBY
3NBZ
3NC0
3NC1
3ZJY
4C0Q
4GMX
4GPT
4HAT
4HAU
4HAV
4HAW
4HAX
4HAY
4HAZ
4HB0
4HB2
4HB3
4HB4
4OL0
4WVF
5CIQ
5CIT
5CIW
5CJ2
5CLL
5CLQ
5DH9
5DHA
5DHF
5DI9
5DIF
5DIS
5DLQ
5FYQ
5JLJ
5UWH
5UWI
5UWJ
5UWO
5UWP
5UWQ
5UWR
5UWS
5UWT
5UWU
5UWW
5YRO
5YST
5YSU
5YTB
5ZPU
6A38
6A3A
6A3B
6A3C
6A3E
6CIT
6KFT
6LQ9
6M60
6M6X
6Q82
6Q84
6TVO
6X2M
6X2O
6X2P
6X2R
6X2S
6X2U
6X2V
6X2W
6X2X
6X2Y
6XJP
6XJR
6XJS
6XJT
6XJU
7B51
7CND
7DBG
7L5E
7MNP
7MNQ
7MNR
7MNS
7MNT
7MNU
7MNV
7MNW
7MNX
7MNY
7MNZ
7MO0
7MO1
7MO2
7MO3
7MO4
7MO5
7YPZ
8HQ3
8HQ4
8HQ5
8HQ6
8HUF
8HUG
8ITV
8UX1
9B62
1QBK
2H4M
2OT8
2QMR
2Z5J
2Z5K
2Z5M
2Z5N
2Z5O
4FDD
4FQ3
4JLQ
4OO6
5J3V
5TQC
5YVG
5YVH
5YVI
7CYL
7VPW
8SGH
Enriched GO Terms of Interacting Partners
?
Small GTPase Binding
Nuclear Transport
Nucleocytoplasmic Transport
Nuclear Pore
Protein Import Into Nucleus
Import Into Nucleus
Intracellular Protein Transport
Protein Localization To Nucleus
Nucleus
Nuclear Export
Nuclear Envelope
Establishment Of Localization In Cell
Intracellular Transport
Protein Transport
Nucleoplasm
Cellular Localization
Protein Export From Nucleus
Nuclear Import Signal Receptor Activity
Protein Localization To Organelle
Establishment Of Protein Localization To Organelle
Establishment Of Protein Localization
Intracellular Protein Localization
RNA Transport
Cytoplasm
Nuclear Export Signal Receptor Activity
Nuclear Membrane
Nucleobase-containing Compound Transport
Nuclear Localization Sequence Binding
Cytosol
Ribosomal Protein Import Into Nucleus
Regulation Of Nucleocytoplasmic Transport
MRNA Transport
RNA Export From Nucleus
Protein-containing Complex
SMAD Binding
NLS-bearing Protein Import Into Nucleus
Protein Binding
Nuclear Inclusion Body
Homomeric SMAD Protein Complex
Cytoplasmic Periphery Of The Nuclear Pore Complex
Response To Growth Factor
Mitotic Spindle Organization
I-SMAD Binding
Regulation Of Intracellular Transport
Cellular Response To Growth Factor Stimulus
Negative Regulation Of RNA Export From Nucleus
SUMO Ligase Complex
Nuclear Pore Cytoplasmic Filaments
Microtubule Cytoskeleton Organization Involved In Mitosis
Regulation Of Cell Cycle
Nuclear Transport
Nucleocytoplasmic Transport
Import Into Nucleus
Nuclear Export
Nuclear Inclusion Body
RNA Export From Nucleus
RNA Transport
Nuclear Pore
Nucleobase-containing Compound Transport
Protein Import Into Nucleus
MRNA Transport
Ribonucleoprotein Complex
Protein Localization To Nucleus
Establishment Of Protein Localization To Organelle
RNA Binding
Nuclear Envelope
Cellular Localization
Intracellular Transport
Nuclear Pore Nuclear Basket
Nucleoplasm
Intracellular Protein Transport
Establishment Of Localization In Cell
Nuclear Localization Sequence Binding
Structural Constituent Of Nuclear Pore
Protein Localization To Organelle
Establishment Of Protein Localization
Nucleus
Cytosolic Ribosome
Nuclear Pore Cytoplasmic Filaments
Negative Regulation Of RNA Export From Nucleus
Regulation Of Nucleocytoplasmic Transport
Protein Transport
MRNA 3'-UTR Binding
Cytosol
Negative Regulation Of Ubiquitin Protein Ligase Activity
Intracellular Protein Localization
Nuclear Pore Complex Assembly
MRNA Export From Nucleus
Negative Regulation Of Ubiquitin-protein Transferase Activity
Nuclear Export Signal Receptor Activity
Ubiquitin Ligase Inhibitor Activity
Nuclear Pore Organization
MRNA Binding
Nuclear Periphery
Regulation Of RNA Export From Nucleus
Regulation Of Intracellular Transport
Pore Complex Assembly
Protein-containing Complex Assembly
Positive Regulation Of Telomere Maintenance Via Telomerase
Poly(A)+ MRNA Export From Nucleus
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Tagcloud (Difference)
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Tagcloud (Intersection)
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