RAB3C and FKBP2

Number of citations of the paper that reports this interaction (PubMedID 22956769)
74

Data Source:
BioGRID (pull down)

		RAB3C	FKBP2
Description		RAB3C, member RAS oncogene family	FKBP prolyl isomerase 2
Image
GO Annotations	Cellular Component	Endosome Plasma Membrane Synaptic Vesicle Membrane Vesicle Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Isomerase Activity
	Biological Process	Exocytosis Protein Transport Regulation Of Exocytosis Antigen Processing And Presentation
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Breast cancer ( 23535729 29059683) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)	Bipolar disorder ( 34002096) Crohn's disease ( 28067908) Fruit consumption ( 32066663)
Interacting Genes		7 interacting genes: CRYAA FKBP2 RABIF REP15 RIMS2 RPH3AL VRTN	14 interacting genes: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN2 UBQLN4 VAMP2
Entrez ID		115827	2286
HPRD ID		06704	01742
Ensembl ID		ENSG00000152932	ENSG00000173486
Uniprot IDs		Q96E17	A0A494C1N0 P26885 Q53XJ5
PDB IDs		6Y7G	2PBC 4NNR
Enriched GO Terms of Interacting Partners?			Polyubiquitin Modification-dependent Protein Binding Regulation Of Protein Catabolic Process Positive Regulation Of ERAD Pathway Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway Regulation Of Cellular Response To Stress Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Localization To Cell Cortex Regulation Of Proteolysis Regulation Of Macroautophagy Positive Regulation Of Protein Catabolic Process Regulation Of Protein Localization To Cell Cortex Autophagosome Organelle Organization Autophagosome Assembly Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Catabolic Process Myosin V Binding Autophagosome Organization Autophagy Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Cytosol Regulation Of Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Metabolic Process Spectrin Binding Regulation Of Autophagy Perinuclear Region Of Cytoplasm Cortical Actin Cytoskeleton Organization Negative Regulation Of Transport Vacuole Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Establishment Of Protein Localization Trans-Golgi Network Cytoplasmic Vesicle Exocytosis Positive Regulation Of Proteolysis Cortical Cytoskeleton Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Peptidyl-cysteine Methylation Negative Regulation Of Store-operated Calcium Channel Activity Response To Endoplasmic Reticulum Stress Regulation Of Vesicle-mediated Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?