RAB3C and REP15

Number of citations of the paper that reports this interaction (PubMedID 35871249)
67

Data Source:
BioGRID (pull down)

		RAB3C	REP15
Description		RAB3C, member RAS oncogene family	RAB15 effector protein
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GO Annotations	Cellular Component	Endosome Plasma Membrane Synaptic Vesicle Membrane Vesicle Perinuclear Region Of Cytoplasm	Endosome Endosome Membrane Membrane Early Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding	Protein Binding
	Biological Process	Exocytosis Protein Transport Regulation Of Exocytosis Antigen Processing And Presentation	Receptor Recycling Transferrin Transport
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Breast cancer ( 23535729 29059683) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)
Interacting Genes		7 interacting genes: CRYAA FKBP2 RABIF REP15 RIMS2 RPH3AL VRTN	9 interacting genes: ARID3A GNG11 RAB15 RAB34 RAB3A RAB3C RAB3D ZRSR2 ZRSR2P1
Entrez ID		115827	387849
HPRD ID		06704	18804
Ensembl ID		ENSG00000152932	ENSG00000174236
Uniprot IDs		Q96E17	Q6BDI9
PDB IDs		6Y7G	8A4A 8A4B 8A4C
Enriched GO Terms of Interacting Partners?			GTP-dependent Protein Binding GTPase Activity Myosin V Binding GTP Binding Regulation Of Exocytosis Positive Regulation Of Regulated Secretory Pathway Exocytosis Pre-mRNA 3'-splice Site Binding U2AF Complex Positive Regulation Of Exocytosis Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Secretion Vesicle Protein Transport Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Vesicle-mediated Transport Regulation Of Secretion Establishment Of Protein Localization Perinuclear Region Of Cytoplasm Lysosome Localization Positive Regulation Of Secretion By Cell Metal Ion Binding Regulation Of Presynaptic Dense Core Granule Exocytosis Positive Regulation Of Secretion Evoked Neurotransmitter Secretion Hydrolase Activity Nucleotide Binding Intracellular Protein Localization Sensory Perception Of Touch Antigen Processing And Presentation Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Regulation Of Dense Core Granule Exocytosis Zymogen Granule Clathrin-sculpted Glutamate Transport Vesicle Membrane Acrosomal Vesicle Exocytosis Clathrin-sculpted Monoamine Transport Vesicle Membrane Constitutive Secretory Pathway Cytosolic Ciliogenesis Regulation Of Plasma Membrane Repair Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Macropinocytosis Spliceosomal Complex Synaptic Vesicle Maturation Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Maintenance Of Presynaptic Active Zone Structure MRNA Splicing, Via Spliceosome Secretory Vesicle
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