SYTL1 and RAB8A

Number of citations of the paper that reports this interaction (PMID 23140275)
3

Data Source:
BioGRID (pull down)

		SYTL1	RAB8A
Gene Name		synaptotagmin-like 1	RAB8A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Extrinsic Component Of Plasma Membrane Melanosome Extracellular Vesicular Exosome	Golgi Membrane Nucleus Nucleoplasm Nucleolus Centrosome Cytosol Plasma Membrane Cilium Synaptic Vesicle Postsynaptic Density Trans-Golgi Network Transport Vesicle Dendrite Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Nonmotile Primary Cilium Ciliary Basal Body Neuronal Cell Body Phagocytic Vesicle Recycling Endosome Membrane Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Protein Binding Rab GTPase Binding Neurexin Family Protein Binding	GTPase Activity Protein Binding GTP Binding Rab GTPase Binding GDP Binding Protein Kinase Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Organelle Organization Axonogenesis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Cilium Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Membrane Organization Protein Localization To Plasma Membrane
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium G2/M Transition Assembly of the primary cilium Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: NCF1 NCF2 NRXN1 RAB27A RAB27B RAB8A	20 interactors: BAG6 BIRC6 GDI2 MAP4K2 MDM2 MYO5B MYO5C OCRL ODF2 OPTN PDE6D PQBP1 RAB3IP RABIF RIMS2 RPH3A RPH3AL SYTL1 SYTL4 TFRC
Entrez ID		84958	4218
HPRD ID		12156	01296
Ensembl ID		ENSG00000142765
Uniprot IDs		Q8IYJ3	B4DEK7 P61006
PDB IDs			3QBT 3TNF
Enriched GO Terms of Interacting Partners?		Vesicle Localization Multivesicular Body Sorting Pathway Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Organelle Localization Protein Secretion Secretion By Cell Cellular Protein Localization Respiratory Burst Regulation Of Exocytosis Establishment Of Protein Localization Superoxide Anion Generation Secretion Regulation Of Secretion Establishment Of Vesicle Localization Ras Protein Signal Transduction Protein Localization Leukocyte Mediated Cytotoxicity Establishment Of Localization In Cell Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Intracellular Protein Transport Antigen Processing And Presentation Melanosome Localization Superoxide Metabolic Process Establishment Of Organelle Localization Regulation Of Cellular Localization Phagosome Maturation Exocytosis Cellular Localization Protein Localization To Membrane Cellular Defense Response Regulation Of Vesicle-mediated Transport Cellular Pigmentation Positive Regulation Of Exocytosis Signal Transduction Protein Transport Signaling Cell Communication Intracellular Transport Positive Regulation Of Constitutive Secretory Pathway Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Complement-dependent Cytotoxicity Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Synaptic Transmission	Establishment Of Protein Localization Protein Localization Protein Transport Vesicle-mediated Transport Cellular Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Intracellular Transport Exocytosis Regulation Of Exocytosis Regulation Of Catalytic Activity Golgi To Plasma Membrane Transport Regulation Of Signaling Intracellular Signal Transduction Secretion By Cell Protein Localization To Organelle Cellular Response To UV-C Cellular Response To Vitamin B1 Establishment Of Protein Localization To Membrane Regulation Of Signal Transduction Cell Cycle Process Secretion Mitotic Cell Cycle Process Negative Regulation Of Signaling Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Transport Organelle Organization Post-Golgi Vesicle-mediated Transport Positive Regulation Of GTPase Activity Negative Regulation Of Proteolysis Mitotic Cell Cycle Protein Localization To Membrane Negative Regulation Of Protein Processing Traversing Start Control Point Of Mitotic Cell Cycle Multivesicular Body Sorting Pathway Negative Regulation Of Receptor Recycling Regulation Of Vesicle-mediated Transport Regulation Of GTPase Activity Response To Vitamin B1 Response To Ether Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Signal Transduction By P53 Class Mediator Cell Cycle Regulation Of Protein Processing G2/M Transition Of Mitotic Cell Cycle Membrane Organization Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity
Tagcloud ?			apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular
Tagcloud (Difference) ?			apical assemble cdc42 directs exchange exocyst exocytosis gef generate guanine hypothesized interconnection lumen machineries must novo organs par3 polarity polarization polarize polarized rab11a rabin8 revealing traffic tuba vesicular
Tagcloud (Intersection) ?