SYTL1 and RAB27B

Number of citations of the paper that reports this interaction (PMID 11980908)
70

Data Source:
BioGRID (two hybrid)

		SYTL1	RAB27B
Gene Name		synaptotagmin-like 1	RAB27B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Extrinsic Component Of Plasma Membrane Melanosome Extracellular Vesicular Exosome	Golgi Stack Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Neurexin Family Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Multivesicular Body Sorting Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: NCF1 NCF2 NRXN1 RAB27A RAB27B RAB8A	8 interactors: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		84958	5874
HPRD ID		12156	04846
Ensembl ID		ENSG00000142765	ENSG00000041353
Uniprot IDs		Q8IYJ3	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?		Vesicle Localization Multivesicular Body Sorting Pathway Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Organelle Localization Protein Secretion Secretion By Cell Cellular Protein Localization Respiratory Burst Regulation Of Exocytosis Establishment Of Protein Localization Superoxide Anion Generation Secretion Regulation Of Secretion Establishment Of Vesicle Localization Ras Protein Signal Transduction Protein Localization Leukocyte Mediated Cytotoxicity Establishment Of Localization In Cell Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Intracellular Protein Transport Antigen Processing And Presentation Melanosome Localization Superoxide Metabolic Process Establishment Of Organelle Localization Regulation Of Cellular Localization Phagosome Maturation Exocytosis Cellular Localization Protein Localization To Membrane Cellular Defense Response Regulation Of Vesicle-mediated Transport Cellular Pigmentation Positive Regulation Of Exocytosis Signal Transduction Protein Transport Signaling Cell Communication Intracellular Transport Positive Regulation Of Constitutive Secretory Pathway Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Complement-dependent Cytotoxicity Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Synaptic Transmission	Exocytosis Secretion By Cell Secretion Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Positive Regulation Of Secretion Protein Localization Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Transport Transport Positive Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Deoxyhypusine Biosynthetic Process From Spermidine Granuloma Formation Spermidine Catabolic Process Multivesicular Body Sorting Pathway Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Catabolic Process Positive Regulation Of Protein Secretion Glucose Homeostasis Natural Killer Cell Degranulation Regulation Of Cellular Localization Chronic Inflammatory Response Positive Regulation Of Mucus Secretion Germinal Center Formation Positive Regulation Of Protein Transport Regulation Of Mucus Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Protein Secretion Natural Killer Cell Activation Involved In Immune Response Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of Mast Cell Degranulation Regulation Of Cell Activation Polyamine Metabolic Process Leukocyte Mediated Cytotoxicity Regulation Of Mast Cell Activation Melanocyte Differentiation Negative Regulation Of Insulin Secretion Regulation Of Regulated Secretory Pathway Melanosome Localization Leukocyte Degranulation Negative Regulation Of Peptide Secretion
Tagcloud ?			7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Difference) ?			7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Intersection) ?