SELENOK and IL10RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SELENOK	IL10RA
Description		selenoprotein K	interleukin 10 receptor subunit alpha
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Monoatomic Ion Transport Calcium Ion Transport Response To Oxidative Stress Macrophage Derived Foam Cell Differentiation Protein Palmitoylation Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production T Cell Proliferation Positive Regulation Of T Cell Proliferation Respiratory Burst After Phagocytosis Regulation Of Calcium-mediated Signaling Regulation Of Protein Transport Establishment Of Localization In Cell Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Positive Regulation Of Monocyte Chemotactic Protein-1 Production T Cell Migration Positive Regulation Of Neutrophil Migration Neutrophil Migration Positive Regulation Of T Cell Migration	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Inflammatory Response Regulation Of Synapse Organization Intestinal Epithelial Structure Maintenance Ubiquitin-dependent Endocytosis Interleukin-10-mediated Signaling Pathway
Pathways			Interleukin-10 signaling Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		42 interacting genes: AMIGO1 AQP6 BIK C6orf47 CLN8 CNR2 COMT CPLX4 CREB3 ERBB2 ERBB3 ERBB4 ERGIC3 FAM209A FFAR2 FKBP7 GLP1R GORAB GPR35 GPX8 IL10RA KLHDC2 LMNA MFSD6 MMD MRM1 MTIF3 MUC1 REEP4 RNF19B SAR1A SLC10A1 SLC10A6 SLC18A1 SLC30A8 SLC35E3 SLC35H1 STMN4 STOM TMEM31 TMPRSS2 TMX2	20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		58515	3587
HPRD ID		07448	00911
Ensembl ID		ENSG00000113811	ENSG00000110324
Uniprot IDs		Q9Y6D0	Q13651
PDB IDs		6DO3	1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
Enriched GO Terms of Interacting Partners?		Membrane ERBB3:ERBB2 Complex Neuregulin Receptor Activity ERBB2 Signaling Pathway ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Bile Acid:sodium Symporter Activity Norepinephrine Transport ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway	Interleukin-10-mediated Signaling Pathway Membrane Response To Inactivity Type III Interferon-mediated Signaling Pathway
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