SELENOK and RNF19B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SELENOK	RNF19B
Description		selenoprotein K	ring finger protein 19B
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Cytolytic Granule
	Molecular Function	Protein Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Conjugating Enzyme Binding Ubiquitin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Monoatomic Ion Transport Calcium Ion Transport Response To Oxidative Stress Macrophage Derived Foam Cell Differentiation Protein Palmitoylation Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production T Cell Proliferation Positive Regulation Of T Cell Proliferation Respiratory Burst After Phagocytosis Regulation Of Calcium-mediated Signaling Regulation Of Protein Transport Establishment Of Localization In Cell Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Positive Regulation Of Monocyte Chemotactic Protein-1 Production T Cell Migration Positive Regulation Of Neutrophil Migration Neutrophil Migration Positive Regulation Of T Cell Migration	Adaptive Immune Response Immune System Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Natural Killer Cell Mediated Cytotoxicity Protein Autoubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		42 interacting genes: AMIGO1 AQP6 BIK C6orf47 CLN8 CNR2 COMT CPLX4 CREB3 ERBB2 ERBB3 ERBB4 ERGIC3 FAM209A FFAR2 FKBP7 GLP1R GORAB GPR35 GPX8 IL10RA KLHDC2 LMNA MFSD6 MMD MRM1 MTIF3 MUC1 REEP4 RNF19B SAR1A SLC10A1 SLC10A6 SLC18A1 SLC30A8 SLC35E3 SLC35H1 STMN4 STOM TMEM31 TMPRSS2 TMX2	30 interacting genes: APOL3 ASGR1 CDIPT CLEC1A DHODH FDPS GIMAP5 GOSR2 ICMT MEST MS4A1 NIPAL4 PPP1CC RAP1GDS1 SACM1L SEC22A SEC23A SELENOK SLC30A3 SLC61A1 TAP1 TMEM100 TMEM120B TMEM208 TMEM31 TNF TSPAN2 UBE2D2 UBE2D3 UBE2L3
Entrez ID		58515	127544
HPRD ID		07448	13725
Ensembl ID		ENSG00000113811	ENSG00000116514
Uniprot IDs		Q9Y6D0	Q6ZMZ0
PDB IDs		6DO3
Enriched GO Terms of Interacting Partners?		Membrane ERBB3:ERBB2 Complex Neuregulin Receptor Activity ERBB2 Signaling Pathway ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Bile Acid:sodium Symporter Activity Norepinephrine Transport ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Ubiquitin Conjugating Enzyme Activity
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