RPRD1B and TNPO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPRD1B	TNPO2
Description		regulation of nuclear pre-mRNA domain containing 1B	transportin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Preinitiation Complex	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding RNA Polymerase II C-terminal Domain Binding	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	RNA Polymerase II Promoter Clearance Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing Positive Regulation Of Transcription By RNA Polymerase II	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport Negative Regulation Of Muscle Cell Differentiation
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS			Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		22 interacting genes: BIN3 CDCA8 DDIT4L EIF4ENIF1 HMG20A HMGB3 HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 SPG21 STAT3 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C WEE2-AS1	54 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CEBPA CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RBM45 REDIC1 RIPK4 RNF10 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C
Entrez ID		58490	30000
HPRD ID		08513	04301
Ensembl ID		ENSG00000101413	ENSG00000105576
Uniprot IDs		Q9NQG5	O14787 Q05D48
PDB IDs		4FLA 4FU3 4HFG 4NAD 4Q94 4Q96 9B9L
Enriched GO Terms of Interacting Partners?		Import Into Nucleus Protein Import Into Nucleus Nuclear Transport Nucleocytoplasmic Transport Cellular Localization Intracellular Protein Transport Establishment Of Protein Localization To Organelle Intracellular Transport Protein Localization To Nucleus Protein Localization To Organelle Membrane Organization Negative Regulation Of Cell Differentiation Nuclear Import Signal Receptor Activity Establishment Of Localization In Cell Nuclear Export Negative Regulation Of Developmental Process Astrocyte Differentiation Intracellular Protein Localization Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair SUMO Conjugating Enzyme Activity Actin Cortical Patch Localization Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA	Identical Protein Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Protein Homodimerization Activity
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