RPRD1B and PFDN6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPRD1B	PFDN6
Description		regulation of nuclear pre-mRNA domain containing 1B	prefoldin subunit 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Preinitiation Complex	Cytoplasm Prefoldin Complex Protein-containing Complex Protein Folding Chaperone Complex RPAP3/R2TP/prefoldin-like Complex
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding RNA Polymerase II C-terminal Domain Binding	Amyloid-beta Binding Protein Binding Unfolded Protein Binding Protein-folding Chaperone Binding
	Biological Process	RNA Polymerase II Promoter Clearance Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing Positive Regulation Of Transcription By RNA Polymerase II	Protein Folding Protein Stabilization Chaperone-mediated Protein Complex Assembly Negative Regulation Of Amyloid Fibril Formation
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		22 interacting genes: BIN3 CDCA8 DDIT4L EIF4ENIF1 HMG20A HMGB3 HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 SPG21 STAT3 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C WEE2-AS1	13 interacting genes: AIMP2 B4GALT2 CCHCR1 CEBPA CEBPG FBXO2 KANK2 KIFC3 MAGEB4 MBD3 PFDN5 RPRD1B THAP11
Entrez ID		58490	10471
HPRD ID		08513	16135
Ensembl ID		ENSG00000101413	ENSG00000204220
Uniprot IDs		Q9NQG5	O15212 Q5STK2
PDB IDs		4FLA 4FU3 4HFG 4NAD 4Q94 4Q96 9B9L	6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Import Into Nucleus Protein Import Into Nucleus Nuclear Transport Nucleocytoplasmic Transport Cellular Localization Intracellular Protein Transport Establishment Of Protein Localization To Organelle Intracellular Transport Protein Localization To Nucleus Protein Localization To Organelle Membrane Organization Negative Regulation Of Cell Differentiation Nuclear Import Signal Receptor Activity Establishment Of Localization In Cell Nuclear Export Negative Regulation Of Developmental Process Astrocyte Differentiation Intracellular Protein Localization Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair SUMO Conjugating Enzyme Activity Actin Cortical Patch Localization Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?