RPRD1B and BIN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPRD1B	BIN3
Description		regulation of nuclear pre-mRNA domain containing 1B	bridging integrator 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Preinitiation Complex	Cytoplasm Cytoskeleton Actin Cytoskeleton
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding RNA Polymerase II C-terminal Domain Binding	Protein Binding Cytoskeletal Anchor Activity Lipid Binding
	Biological Process	RNA Polymerase II Promoter Clearance Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing Positive Regulation Of Transcription By RNA Polymerase II	Endocytosis Actin Filament Organization Intracellular Protein Localization Unidimensional Cell Growth Regulation Of Lamellipodium Assembly Myoblast Migration Involved In Skeletal Muscle Regeneration Skeletal Muscle Tissue Regeneration Developmental Growth Skeletal Muscle Fiber Development Cell Division Actin Cortical Patch Localization Cytoskeleton-dependent Cytokinesis Plasma Membrane Tubulation
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS			Cataracts ( 34127677) Estimated glomerular filtration rate ( 31152163) Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Heel bone mineral density ( 30598549) Parkinson's disease ( 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		22 interacting genes: BIN3 CDCA8 DDIT4L EIF4ENIF1 HMG20A HMGB3 HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 SPG21 STAT3 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C WEE2-AS1	9 interacting genes: ABI2 C14orf119 GINS4 NXF1 POLR1C RPRD1B TRIM69 TXLNA UBL5
Entrez ID		58490	55909
HPRD ID		08513	05904
Ensembl ID		ENSG00000101413	ENSG00000147439
Uniprot IDs		Q9NQG5	E5RHU4 H7BYV6 Q9NQY0
PDB IDs		4FLA 4FU3 4HFG 4NAD 4Q94 4Q96 9B9L
Enriched GO Terms of Interacting Partners?		Import Into Nucleus Protein Import Into Nucleus Nuclear Transport Nucleocytoplasmic Transport Cellular Localization Intracellular Protein Transport Establishment Of Protein Localization To Organelle Intracellular Transport Protein Localization To Nucleus Protein Localization To Organelle Membrane Organization Negative Regulation Of Cell Differentiation Nuclear Import Signal Receptor Activity Establishment Of Localization In Cell Nuclear Export Negative Regulation Of Developmental Process Astrocyte Differentiation Intracellular Protein Localization Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair SUMO Conjugating Enzyme Activity Actin Cortical Patch Localization Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
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