DECR2

Description		2,4-dienoyl-CoA reductase 2
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GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Cytosol
	Molecular Function	Protein Binding 2,4-dienoyl-CoA Reductase (NADPH) Activity Oxidoreductase Activity Trans-2-enoyl-CoA Reductase (NADPH) Activity Protein-containing Complex Binding GTPase Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Body mass index ( 26426971) Hodgkin's lymphoma ( 34216518) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		11 interacting genes: APP C14orf119 EP300 NEDD4L OSGIN1 PEX5 TRIM55 TRIM63 UBC USP11 VPS26C
Entrez ID		26063
HPRD ID		16789
Ensembl ID		ENSG00000242612
Uniprot IDs		Q9NUI1
PDB IDs		4FC6 4FC7
Enriched GO Terms of Interacting Partners?		Regulation Of Glycolytic Process Post-translational Protein Modification Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Protein Modification Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Growth Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Peptidyl-lysine Propionylation Swimming Canonical NF-kappaB Signal Transduction Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Receptor Metabolic Process Protein Monoubiquitination Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Myeloid Cell Development Regulation Of Multicellular Organism Growth Acetylcholine Receptor Activator Activity Response To Interleukin-1 Regulation Of Developmental Growth Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Ubiquitin Protein Ligase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation PTB Domain Binding Collateral Sprouting In Absence Of Injury
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