DECR2 and C14orf119

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DECR2	C14orf119
Description		2,4-dienoyl-CoA reductase 2	chromosome 14 open reading frame 119
Image			No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Cytosol	Mitochondrion Cytosol
	Molecular Function	Protein Binding 2,4-dienoyl-CoA Reductase (NADPH) Activity Oxidoreductase Activity Trans-2-enoyl-CoA Reductase (NADPH) Activity Protein-containing Complex Binding GTPase Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Body mass index ( 26426971) Hodgkin's lymphoma ( 34216518) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		11 interacting genes: APP C14orf119 EP300 NEDD4L OSGIN1 PEX5 TRIM55 TRIM63 UBC USP11 VPS26C	56 interacting genes: ACTN4 ARID3C ARID5A AUNIP BEND7 BIN3 C1QTNF1 CCND3 CDC14A CHMP1A CLPP CTAG1A CTAG1B DDIT4L DECR2 DYNLL1 DYNLL2 HES6 HLX HMG20B ITGB3BP KHDC4 KRT4 KRT78 KRTAP13-3 LASP1 LDB2 LENG1 LRRCC1 MEOX1 MORN3 MYF5 NIF3L1 NME4 NRIP3 NUP54 NUP62 PBX4 PHACTR1 PINX1 RAB3IL1 REL RHOU RND3 RNF4 RPIA SMCP SNX8 SSX4 SSX4B STN1 SYCP3 TEX35 TLE5 UBXN11 WASHC1
Entrez ID		26063	55017
HPRD ID		16789	16595
Ensembl ID		ENSG00000242612	ENSG00000179933
Uniprot IDs		Q9NUI1	Q9NWQ9
PDB IDs		4FC6 4FC7
Enriched GO Terms of Interacting Partners?		Regulation Of Glycolytic Process Post-translational Protein Modification Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Protein Modification Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Growth Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Peptidyl-lysine Propionylation Swimming Canonical NF-kappaB Signal Transduction Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Receptor Metabolic Process Protein Monoubiquitination Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Myeloid Cell Development Regulation Of Multicellular Organism Growth Acetylcholine Receptor Activator Activity Response To Interleukin-1 Regulation Of Developmental Growth Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Ubiquitin Protein Ligase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation PTB Domain Binding Collateral Sprouting In Absence Of Injury	Protein Binding
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