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PTPRM and PPFIBP1
Number of citations of the paper that reports this interaction (PMID
9624153
)
49
Data Source:
HPRD
(in vitro)
PTPRM
PPFIBP1
Gene Name
protein tyrosine phosphatase, receptor type, M
PTPRF interacting protein, binding protein 1 (liprin beta 1)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Integral Component Of Plasma Membrane
Cell-cell Junction
Cell-cell Adherens Junction
Lamellipodium
Perinuclear Region Of Cytoplasm
Plasma Membrane
Focal Adhesion
Molecular Function
Protein Tyrosine Phosphatase Activity
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Protein Binding
Identical Protein Binding
Cadherin Binding
Biological Process
Negative Regulation Of Endothelial Cell Proliferation
Protein Dephosphorylation
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Signal Transduction
Negative Regulation Of Endothelial Cell Migration
Retina Layer Formation
Negative Regulation Of Angiogenesis
Neuron Projection Development
Retinal Ganglion Cell Axon Guidance
Peptidyl-tyrosine Dephosphorylation
Response To Drug
Positive Regulation Of Vasodilation
Cell Adhesion
Pathways
Drugs
Diseases
GWAS
Dialysis-related mortality (
21546767
)
Protein-Protein Interactions
9 interactors:
CDH1
CTNNB1
CTNND1
GNB2L1
PCSK5
PPFIBP1
PTPRA
PTPRK
PTPRS
7 interactors:
PPFIA1
PPFIA2
PPFIA3
PTPRM
S100A4
YWHAG
YWHAQ
Entrez ID
5797
8496
HPRD ID
01479
04390
Ensembl ID
ENSG00000173482
ENSG00000110841
Uniprot IDs
E7EVX9
P28827
Q86W92
PDB IDs
1RPM
2C9A
2V5Y
Enriched GO Terms of Interacting Partners
?
Adherens Junction Organization
Cell Junction Assembly
Cell-cell Junction Organization
Cellular Response To Indole-3-methanol
Cell Adhesion
Regulation Of Wnt Signaling Pathway
Digestive Tract Development
Digestive System Development
Protein Localization To Cell Surface
Regulation Of Protein Localization To Cell Surface
Peptidyl-tyrosine Dephosphorylation
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Embryonic Development
Regulation Of Canonical Wnt Signaling Pathway
Protein Dephosphorylation
Brain Development
Adherens Junction Assembly
Regulation Of Epithelial Cell Proliferation
Head Development
Epithelial Cell Morphogenesis
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Regulation Of Cell Cycle
Regulation Of Morphogenesis Of A Branching Structure
Cellular Response To Organic Substance
Central Nervous System Development
Multicellular Organismal Development
Execution Phase Of Apoptosis
Anatomical Structure Development
Renin Secretion Into Blood Stream
Negative Regulation Of Signal Transduction
Forebrain Development
Embryo Development
Dephosphorylation
Lens Development In Camera-type Eye
Cellular Response To Organonitrogen Compound
Negative Regulation Of Signaling
Nervous System Development
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Schwann Cell Proliferation
Cellular Response To Insulin-like Growth Factor Stimulus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of CAMP Catabolic Process
Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure
Single Organismal Cell-cell Adhesion
Regulation Of Embryonic Development
Developmental Process
Anatomical Structure Morphogenesis
Negative Regulation Of Epithelial Cell Proliferation
Glutamate Secretion
Acid Secretion
Dicarboxylic Acid Transport
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Amino Acid Transport
Neurotransmitter Transport
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Carboxylic Acid Transport
Organic Acid Transport
Establishment Of Localization In Cell
Positive Regulation Of Mitochondrion Organization
Cellular Localization
Organic Anion Transport
Secretion By Cell
Regulation Of Mitochondrion Organization
Synaptic Transmission
Secretion
Anion Transport
Regulation Of Establishment Of Protein Localization
Signaling
Regulation Of Synaptic Plasticity
Cell-matrix Adhesion
Cell Communication
Regulation Of Protein Localization
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Cell-substrate Adhesion
Cell-cell Signaling
Regulation Of Organelle Organization
Positive Regulation Of Intracellular Transport
Regulation Of Cellular Localization
Negative Regulation Of Stress Fiber Assembly
Regulation Of Synaptic Transmission
Negative Regulation Of Actin Filament Bundle Assembly
Regulation Of Short-term Neuronal Synaptic Plasticity
Cell Adhesion
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Apoptotic Signaling Pathway
Positive Regulation Of Signal Transduction
Transport
Positive Regulation Of Organelle Organization
Negative Regulation Of Protein Localization To Plasma Membrane
Protein Targeting
Retinal Ganglion Cell Axon Guidance
Regulation Of Intracellular Transport
Regulation Of Signaling
Retina Layer Formation
Tagcloud
?
12q21
18p11
20q12
7q31
aberrations
amplified
braf
chromosomal
colorectal
connected
covering
deleted
deletions
gains
glioma
hypermethylated
losses
methylator
molecularly
oncogenes
phosphatases
ptprq
ptprt
ptprz1
ptps
sporadic
suppressors
unbalanced
z1
Tagcloud (Difference)
?
12q21
18p11
20q12
7q31
aberrations
amplified
braf
chromosomal
colorectal
connected
covering
deleted
deletions
gains
glioma
hypermethylated
losses
methylator
molecularly
oncogenes
phosphatases
ptprq
ptprt
ptprz1
ptps
sporadic
suppressors
unbalanced
z1
Tagcloud (Intersection)
?