DHPS and VASH1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		DHPS	VASH1
Description		deoxyhypusine synthase	vasohibin 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Apical Part Of Cell
	Molecular Function	Protein Binding Transferase Activity Deoxyhypusine Synthase Activity Identical Protein Binding	Actin Binding Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Tubulin-tyrosine Carboxypeptidase
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of T Cell Proliferation Glucose Homeostasis Spermidine Catabolic Process Protein Maturation	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Proteolysis Response To Wounding Negative Regulation Of Angiogenesis Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Angiogenesis Regulation Of Cell Cycle Placenta Blood Vessel Development Labyrinthine Layer Blood Vessel Development Negative Regulation Of Lymphangiogenesis Regulation Of Cellular Senescence
Pathways		Hypusine synthesis from eIF5A-lysine	Carboxyterminal post-translational modifications of tubulin
Drugs		1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Platelet distribution width ( 32888494)
Interacting Genes		16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138	1 interacting genes: DHPS
Entrez ID		1725	22846
HPRD ID		02969	12353
Ensembl ID		ENSG00000095059	ENSG00000071246
Uniprot IDs		P49366	Q7L8A9
PDB IDs		1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM 7A6S 7A6T 8A0E 8A0F 8A0G 8PVU 8R3U	6J4U 6J7B 6J8F 6J8N 6J8O 6J91 6J9H 6K81 6LPG 6NVQ 6OCF 6OCG 6OCH 6WSL
Enriched GO Terms of Interacting Partners?		Regulation Of Translational Termination Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Regulation Of Translational Elongation Translation Elongation Factor Activity Regulation Of Protein-containing Complex Disassembly Cytoplasm Positive Regulation Of Protein-containing Complex Disassembly Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process	Spermidine Catabolic Process Polyamine Catabolic Process Deoxyhypusine Synthase Activity Cholesterol Storage Regulation Of Isoprenoid Metabolic Process Spermidine Metabolic Process Glycolipid Transport Sterol Binding Chemical Homeostasis Polyamine Metabolic Process Cholesterol Transfer Activity Intracellular Sterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Lipid Storage Intracellular Lipid Transport Homeostatic Process Cholesterol Binding Macromolecule Biosynthetic Process Biogenic Amine Metabolic Process Cholesterol Transport Amine Metabolic Process Phospholipid Transport Sterol Homeostasis Sterol Transport Azurophil Granule Lumen Lysosomal Lumen Carbohydrate Derivative Transport Cholesterol Homeostasis Positive Regulation Of T Cell Proliferation Cholesterol Metabolic Process Sterol Metabolic Process
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