DHPS and RBP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DHPS	RBP1
Description		deoxyhypusine synthase	retinol binding protein 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Lipid Droplet Cytosol
	Molecular Function	Protein Binding Transferase Activity Deoxyhypusine Synthase Activity Identical Protein Binding	Retinoid Binding Fatty Acid Binding Protein Binding Lipid Binding Retinal Binding Retinol Binding All-trans-retinol Binding
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of T Cell Proliferation Glucose Homeostasis Spermidine Catabolic Process Protein Maturation	Retinoic Acid Biosynthetic Process Vitamin A Metabolic Process Fatty Acid Transport Lipid Homeostasis
Pathways		Hypusine synthesis from eIF5A-lysine	The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport Defective visual phototransduction due to LRAT loss of function
Drugs		1-Guanidinium-7-Aminoheptane	Acitretin
Diseases
GWAS		Platelet distribution width ( 32888494)
Interacting Genes		16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138	18 interacting genes: BRMS1 BRMS1L CYTOR DHPS HDAC1 HDAC2 IKBKG ING1 LRAT LRP2 MED26 RBBP4 RBBP7 SAP30 SIN3A TNFRSF10D TTC19 UBE2J2
Entrez ID		1725	5947
HPRD ID		02969	07036
Ensembl ID		ENSG00000095059	ENSG00000114115
Uniprot IDs		P49366	A0A0A0MQT0 P09455
PDB IDs		1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM 7A6S 7A6T 8A0E 8A0F 8A0G 8PVU 8R3U	5H8T 5H9A 5HA1 5HBS 5LJB 5LJC 5LJD 5LJE 5LJG 5LJH 5LJK 6E5L 6E5T 6E6M 8GD2 8GDM 8GEM 8GEU 8GEV 8GEY
Enriched GO Terms of Interacting Partners?		Regulation Of Translational Termination Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Regulation Of Translational Elongation Translation Elongation Factor Activity Regulation Of Protein-containing Complex Disassembly Cytoplasm Positive Regulation Of Protein-containing Complex Disassembly Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Histone Deacetylase Complex Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion NuRD Complex Regulation Of Cell Fate Specification Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of Cell Fate Commitment Regulation Of Cell Migration Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Developmental Process Histone Deacetylase Binding Regulation Of Cell Motility Regulation Of Locomotion ESC/E(Z) Complex Negative Regulation Of Multicellular Organismal Process Regulation Of Stem Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Lysine Delactylase Activity Fungiform Papilla Formation Negative Regulation Of RNA Metabolic Process NF-kappaB Binding Protein Decrotonylase Activity Histone Decrotonylase Activity Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleosomal DNA Binding Hair Follicle Placode Formation Cellular Response To Dopamine NURF Complex Response To Dopamine Regulation Of Multicellular Organismal Process Positive Regulation Of Gliogenesis Regulation Of Developmental Process Histone Deacetylase Activity, Hydrolytic Mechanism Regulation Of Signal Transduction
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