DHPS and ZNF138

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		DHPS	ZNF138
Description		deoxyhypusine synthase	zinc finger protein 138
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus
	Molecular Function	Protein Binding Transferase Activity Deoxyhypusine Synthase Activity Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of T Cell Proliferation Glucose Homeostasis Spermidine Catabolic Process Protein Maturation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Hypusine synthesis from eIF5A-lysine	Generic Transcription Pathway
Drugs		1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Platelet distribution width ( 32888494)
Interacting Genes		16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138	16 interacting genes: BCCIP DHPS ELOA2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP12-3 LHX6 LMNA MAPK9 MDFI TRIM41 ZBTB8A
Entrez ID		1725	7697
HPRD ID		02969	07244
Ensembl ID		ENSG00000095059	ENSG00000197008
Uniprot IDs		P49366	A0A0A0MRG3 A0A0A0MT90 A2RRP7 C9JHF6 E7EWC5 J3QSS9 P52744
PDB IDs		1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM 7A6S 7A6T 8A0E 8A0F 8A0G 8PVU 8R3U
Enriched GO Terms of Interacting Partners?		Regulation Of Translational Termination Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Regulation Of Translational Elongation Translation Elongation Factor Activity Regulation Of Protein-containing Complex Disassembly Cytoplasm Positive Regulation Of Protein-containing Complex Disassembly Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process	Intermediate Filament Keratin Filament
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?