MAGI3

Gene Name		membrane associated guanylate kinase, WW and PDZ domain containing 3
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Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Tight Junction Membrane
	Molecular Function	Guanylate Kinase Activity Frizzled Binding Protein Binding ATP Binding Protein Complex Scaffold
	Biological Process	Apoptotic Process Viral Process Intracellular Signal Transduction Positive Regulation Of JUN Kinase Activity Nucleotide Phosphorylation
Pathways
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Obesity-related traits ( 23251661)
Protein-protein Interactions		14 interactors: ADRB1 BAI1 DSCAML1 FZD4 FZD7 GRIN2B LATS1 NRCAM PLXNB3 PTEN PTPRB TGFA TNK2 VANGL2
Entrez ID		260425
HPRD ID		11290
Ensembl ID		ENSG00000081026
Uniprot IDs		Q5TCQ9
PDB IDs		3SOE
Enriched GO Terms of Interacting Partners?		Cell Morphogenesis Developmental Process Cell Morphogenesis Involved In Differentiation Neuron Differentiation Anatomical Structure Morphogenesis Cell Differentiation Generation Of Neurons System Development Neurogenesis Signaling Negative Regulation Of Cell Adhesion Cell Communication Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Multicellular Organismal Development Axonogenesis Anatomical Structure Development Neuron Development Axon Development Regulation Of Phosphorus Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Non-canonical Wnt Signaling Pathway Signal Transduction Nervous System Development Neuron Projection Morphogenesis Cell Surface Receptor Signaling Pathway Cell Projection Organization Locomotion Blood Vessel Morphogenesis Negative Regulation Of Cell-substrate Adhesion Regulation Of Phosphorylation Regulation Of Cellular Component Organization Neuron Projection Development Positive Regulation Of Phosphorylation Cardiovascular System Development Positive Regulation Of Protein Modification Process Blood Vessel Development Response To Stimulus Vasculature Development Cellular Response To Stimulus Regulation Of Postsynaptic Membrane Potential Wnt Signaling Pathway Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Multicellular Organismal Response To Stress Regulation Of Cell Adhesion Regulation Of Epithelial Cell Proliferation Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		aberration akt1 akt3 amplifications beyond cbfb competitive confirming deaths deletions discovered erbb2 exome gata3 genomes malignancy map3k1 mexico million notably oestrogen pairs partner pik3ca rearrangements recurrent runx1 somatic vietnam