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POLD4 and POLD1
Number of citations of the paper that reports this interaction (PMID
16510448
)
23
Data Source:
BioGRID
(pull down, pull down)
POLD4
POLD1
Gene Name
polymerase (DNA-directed), delta 4, accessory subunit
polymerase (DNA directed), delta 1, catalytic subunit
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleotide-excision Repair Complex
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Aggresome
Delta DNA Polymerase Complex
Molecular Function
DNA-directed DNA Polymerase Activity
Protein Binding
Nucleotide Binding
DNA Binding
Chromatin Binding
DNA-directed DNA Polymerase Activity
Protein Binding
3'-5'-exodeoxyribonuclease Activity
Metal Ion Binding
4 Iron, 4 Sulfur Cluster Binding
Biological Process
Mitotic Cell Cycle
Telomere Maintenance Via Recombination
Telomere Maintenance
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Telomere Maintenance Via Semi-conservative Replication
DNA Biosynthetic Process
Mitotic Cell Cycle
Telomere Maintenance Via Recombination
Telomere Maintenance
DNA Synthesis Involved In DNA Repair
DNA Catabolic Process, Exonucleolytic
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Base-excision Repair, Gap-filling
Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Response To UV
Telomere Maintenance Via Semi-conservative Replication
Small Molecule Metabolic Process
DNA Replication Proofreading
Fatty Acid Homeostasis
Pathways
Nucleotide Excision Repair
Gap-filling DNA repair synthesis and ligation in TC-NER
Extension of Telomeres
Repair synthesis for gap-filling by DNA polymerase in TC-NER
Leading Strand Synthesis
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
DNA strand elongation
Mismatch Repair
Polymerase switching
Telomere Maintenance
Removal of DNA patch containing abasic residue
Resolution of Abasic Sites (AP sites)
Removal of the Flap Intermediate from the C-strand
Base Excision Repair
Polymerase switching on the C-strand of the telomere
Synthesis of DNA
Chromosome Maintenance
Lagging Strand Synthesis
Processive synthesis on the C-strand of the telomere
Processive synthesis on the lagging strand
S Phase
Telomere C-strand (Lagging Strand) Synthesis
Repair synthesis of patch ~27-30 bases long by DNA polymerase
Cell Cycle, Mitotic
Gap-filling DNA repair synthesis and ligation in GG-NER
Removal of the Flap Intermediate
Global Genomic NER (GG-NER)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
Transcription-coupled NER (TC-NER)
Nucleotide Excision Repair
Gap-filling DNA repair synthesis and ligation in TC-NER
Extension of Telomeres
Repair synthesis for gap-filling by DNA polymerase in TC-NER
Leading Strand Synthesis
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
DNA strand elongation
Mismatch Repair
Polymerase switching
Telomere Maintenance
Cytosolic iron-sulfur cluster assembly
Removal of DNA patch containing abasic residue
Resolution of Abasic Sites (AP sites)
Removal of the Flap Intermediate from the C-strand
Base Excision Repair
Polymerase switching on the C-strand of the telomere
Synthesis of DNA
Chromosome Maintenance
Lagging Strand Synthesis
Processive synthesis on the C-strand of the telomere
Processive synthesis on the lagging strand
S Phase
Telomere C-strand (Lagging Strand) Synthesis
Repair synthesis of patch ~27-30 bases long by DNA polymerase
Cell Cycle, Mitotic
Gap-filling DNA repair synthesis and ligation in GG-NER
Removal of the Flap Intermediate
Global Genomic NER (GG-NER)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
Transcription-coupled NER (TC-NER)
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
7 interactors:
PCNA
POLD1
POLD2
POLD3
POLE
SEC23IP
WRNIP1
16 interactors:
ATR
CCND3
CCNE1
CDK2
CDK4
CHGB
GINS4
KIAA1377
PCNA
POLD2
POLD3
POLD4
TERF2IP
TREX2
WRNIP1
XRCC5
Entrez ID
57804
5424
HPRD ID
17873
08882
Ensembl ID
ENSG00000062822
Uniprot IDs
Q6NSD7
Q9HCU8
M0R2B7
P28340
Q59FA0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nucleotide-excision Repair, DNA Gap Filling
Telomere Maintenance Via Semi-conservative Replication
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Mitotic Recombination
DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
DNA Synthesis Involved In DNA Repair
Telomere Maintenance
DNA Replication
Nucleotide-excision Repair
DNA-dependent DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Mismatch Repair
DNA Repair
DNA Recombination
Cellular Response To DNA Damage Stimulus
DNA Metabolic Process
Cellular Homeostasis
Cellular Response To Stress
Mitotic Cell Cycle
Base-excision Repair, Gap-filling
Chromosome Organization
Cell Cycle Process
Cell Cycle
Homeostatic Process
Organelle Organization
Response To Stress
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Deoxyribonuclease Activity
DNA Replication Proofreading
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Leading Strand Elongation
Regulation Of DNA Replication
Nitrogen Compound Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Regulation Of DNA-dependent DNA Replication Initiation
Cell Cycle Phase Transition
Cellular Response To Stimulus
Translesion Synthesis
Fatty Acid Homeostasis
DNA Replication
DNA Metabolic Process
Telomere Maintenance
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Cellular Response To DNA Damage Stimulus
Telomere Maintenance Via Telomere Lengthening
DNA Repair
Cell Cycle
DNA-dependent DNA Replication
Mitotic Cell Cycle
Nucleotide-excision Repair, DNA Gap Filling
Telomere Maintenance Via Semi-conservative Replication
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Cell Cycle Process
Mitotic Recombination
Cellular Response To Stress
DNA Recombination
DNA Biosynthetic Process
Transcription-coupled Nucleotide-excision Repair
Chromosome Organization
Mismatch Repair
Base-excision Repair
Nucleotide-excision Repair
Response To Stress
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of DNA Replication
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Organelle Organization
Cellular Response To Stimulus
Nitrogen Compound Metabolic Process
Regulation Of DNA-dependent DNA Replication Initiation
Biosynthetic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Mitotic Cell Cycle Process
DNA Synthesis Involved In DNA Repair
Response To Stimulus
Cellular Metabolic Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Homeostatic Process
Cell Division
Cellular Response To Ionizing Radiation
Positive Regulation Of Deoxyribonuclease Activity
Tagcloud
?
19q13
adenoma
arm
atp1a3
bands
bckdha
benign
boundary
breakpoint
chromosome
communication
cosmids
cytogenetic
distal
ercc1
establishment
mapped
mapping
p35
p36
probes
q13
ryr1
subset
sv40
thyroid
transformed
translocations
trpt
Tagcloud (Difference)
?
19q13
adenoma
arm
atp1a3
bands
bckdha
benign
boundary
breakpoint
chromosome
communication
cosmids
cytogenetic
distal
ercc1
establishment
mapped
mapping
p35
p36
probes
q13
ryr1
subset
sv40
thyroid
transformed
translocations
trpt
Tagcloud (Intersection)
?