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POLD4 and WRNIP1
Number of citations of the paper that reports this interaction (PMID
15670210
)
7
Data Source:
HPRD
(in vitro)
POLD4
WRNIP1
Gene Name
polymerase (DNA-directed), delta 4, accessory subunit
Werner helicase interacting protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleus
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
DNA-directed DNA Polymerase Activity
Protein Binding
DNA Binding
Protein Binding
ATP Binding
ATPase Activity
Identical Protein Binding
Metal Ion Binding
Biological Process
Mitotic Cell Cycle
Telomere Maintenance Via Recombination
Telomere Maintenance
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Telomere Maintenance Via Semi-conservative Replication
DNA Biosynthetic Process
DNA Synthesis Involved In DNA Repair
DNA Replication
Regulation Of DNA-dependent DNA Replication Initiation
Pathways
Nucleotide Excision Repair
Gap-filling DNA repair synthesis and ligation in TC-NER
Extension of Telomeres
Repair synthesis for gap-filling by DNA polymerase in TC-NER
Leading Strand Synthesis
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
DNA strand elongation
Mismatch Repair
Polymerase switching
Telomere Maintenance
Removal of DNA patch containing abasic residue
Resolution of Abasic Sites (AP sites)
Removal of the Flap Intermediate from the C-strand
Base Excision Repair
Polymerase switching on the C-strand of the telomere
Synthesis of DNA
Chromosome Maintenance
Lagging Strand Synthesis
Processive synthesis on the C-strand of the telomere
Processive synthesis on the lagging strand
S Phase
Telomere C-strand (Lagging Strand) Synthesis
Repair synthesis of patch ~27-30 bases long by DNA polymerase
Cell Cycle, Mitotic
Gap-filling DNA repair synthesis and ligation in GG-NER
Removal of the Flap Intermediate
Global Genomic NER (GG-NER)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
Transcription-coupled NER (TC-NER)
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
PCNA
POLD1
POLD2
POLD3
POLE
SEC23IP
WRNIP1
8 interactors:
ABL1
DDX58
PIN1
POLD1
POLD2
POLD4
TOLLIP
WRN
Entrez ID
57804
56897
HPRD ID
17873
10494
Ensembl ID
ENSG00000124535
Uniprot IDs
Q6NSD7
Q9HCU8
Q96S55
PDB IDs
3VHS
3VHT
Enriched GO Terms of Interacting Partners
?
Nucleotide-excision Repair, DNA Gap Filling
Telomere Maintenance Via Semi-conservative Replication
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Mitotic Recombination
DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
DNA Synthesis Involved In DNA Repair
Telomere Maintenance
DNA Replication
Nucleotide-excision Repair
DNA-dependent DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Mismatch Repair
DNA Repair
DNA Recombination
Cellular Response To DNA Damage Stimulus
DNA Metabolic Process
Cellular Homeostasis
Cellular Response To Stress
Mitotic Cell Cycle
Base-excision Repair, Gap-filling
Chromosome Organization
Cell Cycle Process
Cell Cycle
Homeostatic Process
Organelle Organization
Response To Stress
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Deoxyribonuclease Activity
DNA Replication Proofreading
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Leading Strand Elongation
Regulation Of DNA Replication
Nitrogen Compound Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Regulation Of DNA-dependent DNA Replication Initiation
Cell Cycle Phase Transition
Cellular Response To Stimulus
Translesion Synthesis
Fatty Acid Homeostasis
Mismatch Repair
Base-excision Repair
Telomere Maintenance
Nucleotide-excision Repair, DNA Gap Filling
DNA-dependent DNA Replication
DNA Biosynthetic Process
Telomere Maintenance Via Semi-conservative Replication
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
Response To Stress
Transcription-coupled Nucleotide-excision Repair
DNA Repair
DNA Recombination
DNA Replication
Cellular Response To DNA Damage Stimulus
Nucleotide-excision Repair
DNA Metabolic Process
DNA Synthesis Involved In DNA Repair
Cell Cycle
Homeostatic Process
Cellular Response To Stimulus
Cellular Homeostasis
Cellular Response To Stress
Mitotic Cell Cycle
Innate Immune Response
Negative Regulation Of Type I Interferon Production
Negative Regulation Of ERK1 And ERK2 Cascade
Chromosome Organization
Response To Stimulus
Cell Cycle Process
DNA Replication Proofreading
Transitional One Stage B Cell Differentiation
Regulation Of Ubiquitin-protein Transferase Activity
Immune Response
Regulation Of Type I Interferon Production
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Defense Response
Regulation Of Cytokine Production
Negative Regulation Of Phospholipase C Activity
Mitochondrial Depolarization
Response To UV
Regulation Of Cell Motility
Regulation Of Growth Rate
Cellular Response To Dopamine
Nucleolus To Nucleoplasm Transport
RIG-I Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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