CATSPER1 and RGS20

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CATSPER1	RGS20
Gene Name		cation channel, sperm associated 1	regulator of G-protein signaling 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Motile Cilium CatSper Complex	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Calcium Activated Cation Channel Activity Voltage-gated Calcium Channel Activity Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Multicellular Organismal Development Spermatogenesis Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Cell Differentiation Sperm Motility Multicellular Organism Reproduction Regulation Of Ion Transmembrane Transport Sperm-egg Recognition Regulation Of Calcium Ion Transport Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Sperm Motility And Taxes Fertilization	Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: ADAMTSL4 AGR2 APOA2 BEGAIN CHIC2 CHRD EFEMP2 EMD KHDRBS2 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MTUS2 NOTCH2NL PLSCR1 PLSCR3 RFX6 RGS20 RIMBP3 SCRG1 SPRY2 TRAF2 TRIP6	33 interactors: ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 OSTM1 OTX1 PTGER3 PTPMT1 PVRL3 STMN2 TBC1D16
Entrez ID		117144	8601
HPRD ID		09396	06225
Ensembl ID		ENSG00000175294	ENSG00000147509
Uniprot IDs		Q8NEC5	H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Phospholipid Scrambling Regulation Of Protein Localization Phospholipid Transport Regulation Of Cellular Localization Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Transport Regulation Of Signaling Regulation Of Protein Localization To Nucleus Glandular Epithelial Cell Differentiation Regulation Of Nucleocytoplasmic Transport BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Pancreatic Epsilon Cell Differentiation Negative Regulation Of Cholesterol Transporter Activity Pancreatic D Cell Differentiation I-kappaB Kinase/NF-kappaB Signaling Regulation Of Intracellular Protein Transport Positive Regulation Of Catalytic Activity Regulation Of Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of JUN Kinase Activity Regulation Of Membrane Lipid Distribution Negative Regulation Of Protein Import Into Nucleus Mucus Secretion Regulation Of Cholesterol Transporter Activity Negative Regulation Of Cholesterol Import Acute Inflammatory Response Regulation Of MAP Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Epithelium Development Cholesterol Homeostasis Lipid Transport Sterol Homeostasis Regulation Of JUN Kinase Activity Negative Regulation Of Protein Localization To Nucleus Lipid Localization Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Lung Goblet Cell Differentiation Regulation Of Cholesterol Import Negative Regulation Of Intracellular Protein Transport Tissue Development Regulation Of Transcription Factor Import Into Nucleus Developmental Process Positive Regulation Of Nucleocytoplasmic Transport Lobar Bronchus Development Release Of Cytoplasmic Sequestered NF-kappaB Diacylglycerol Catabolic Process Lipid Homeostasis	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Keratinocyte Differentiation Epidermis Development Developmental Process Epidermal Cell Differentiation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Organ Development System Development Multicellular Organismal Development Anatomical Structure Development Skin Development Heat Generation G-protein Coupled Receptor Signaling Pathway Cell Differentiation Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Tissue Development Regulation Of CAMP Biosynthetic Process Epithelium Development Regulation Of CAMP Metabolic Process Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Epithelial Cell Differentiation Temperature Homeostasis Membrane Fusion Regulation Of Body Fluid Levels Cell-cell Signaling Negative Regulation Of CAMP Biosynthetic Process Sensory Organ Development Wound Healing Bicarbonate Transport Negative Regulation Of CAMP Metabolic Process Eye Morphogenesis Cell Activation Negative Regulation Of Nucleotide Metabolic Process Acute-phase Response Regulation Of Catalytic Activity Response To Wounding Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation B Cell Cytokine Production Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Isotype Switching To IgG Isotypes Anion Homeostasis
Tagcloud ?		5k3 alpl armitage beadchip bovinesnp50 bull capn1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Difference) ?		5k3 alpl armitage beadchip bovinesnp50 bull capn1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Intersection) ?