CATSPER1 and RIMBP3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CATSPER1	RIMBP3
Gene Name		cation channel, sperm associated 1	RIMS binding protein 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Motile Cilium CatSper Complex
	Molecular Function	Calcium Activated Cation Channel Activity Voltage-gated Calcium Channel Activity Protein Binding
	Biological Process	Multicellular Organismal Development Spermatogenesis Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Cell Differentiation Sperm Motility Multicellular Organism Reproduction Regulation Of Ion Transmembrane Transport Sperm-egg Recognition Regulation Of Calcium Ion Transport Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential
Pathways		Sperm Motility And Taxes Fertilization
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		33 interactors: ADAMTSL4 AGR2 APOA2 BEGAIN CHIC2 CHRD EFEMP2 EMD KHDRBS2 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MTUS2 NOTCH2NL PLSCR1 PLSCR3 RFX6 RGS20 RIMBP3 SCRG1 SPRY2 TRAF2 TRIP6	18 interactors: AES AQP1 ARNT2 CATSPER1 CREB5 CTBP2 DGCR6 DGCR6L DTX2 FANCL MVP NOXA1 POLR1C PPIL1 PRKAA1 PRKAB2 TRAF3IP2 ZNF488
Entrez ID		117144	85376
HPRD ID		09396	13881
Ensembl ID		ENSG00000175294	ENSG00000196622
Uniprot IDs		Q8NEC5	Q9UFD9
PDB IDs			2EGE
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Phospholipid Scrambling Regulation Of Protein Localization Phospholipid Transport Regulation Of Cellular Localization Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Transport Regulation Of Signaling Regulation Of Protein Localization To Nucleus Glandular Epithelial Cell Differentiation Regulation Of Nucleocytoplasmic Transport BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Pancreatic Epsilon Cell Differentiation Negative Regulation Of Cholesterol Transporter Activity Pancreatic D Cell Differentiation I-kappaB Kinase/NF-kappaB Signaling Regulation Of Intracellular Protein Transport Positive Regulation Of Catalytic Activity Regulation Of Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of JUN Kinase Activity Regulation Of Membrane Lipid Distribution Negative Regulation Of Protein Import Into Nucleus Mucus Secretion Regulation Of Cholesterol Transporter Activity Negative Regulation Of Cholesterol Import Acute Inflammatory Response Regulation Of MAP Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Epithelium Development Cholesterol Homeostasis Lipid Transport Sterol Homeostasis Regulation Of JUN Kinase Activity Negative Regulation Of Protein Localization To Nucleus Lipid Localization Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Lung Goblet Cell Differentiation Regulation Of Cholesterol Import Negative Regulation Of Intracellular Protein Transport Tissue Development Regulation Of Transcription Factor Import Into Nucleus Developmental Process Positive Regulation Of Nucleocytoplasmic Transport Lobar Bronchus Development Release Of Cytoplasmic Sequestered NF-kappaB Diacylglycerol Catabolic Process Lipid Homeostasis	Nucleobase-containing Compound Metabolic Process Ammonium Transmembrane Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation RNA Metabolic Process Cellular Response To Hydrogen Peroxide Response To Hypoxia Ammonium Transport Gene Expression Carbon Dioxide Transmembrane Transport Corticotropin Secretion Establishment Or Maintenance Of Actin Cytoskeleton Polarity Nitrogen Compound Metabolic Process Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Negative Regulation Of Glucose Import In Response To Insulin Stimulus Cellular Response To Mercury Ion Cellular Response To Hypoxia Negative Regulation Of Cellular Metabolic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Reactive Oxygen Species Biosynthetic Process Response To Camptothecin Metanephric Proximal Tubule Development Positive Regulation Of Anoikis Cellular Response To Oxygen Levels Regulation Of Cell Proliferation Renal Water Absorption Positive Regulation Of Saliva Secretion Carbon Dioxide Transport Epithelial Fluid Transport Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Fat Cell Differentiation Response To Hydrogen Peroxide Response To Hormone Fatty Acid Biosynthetic Process Response To UV Cellular Response To Organonitrogen Compound Positive Regulation Of Chromatin Binding Renal Water Transport
Tagcloud ?		5k3 alpl armitage beadchip bovinesnp50 bull capn1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Difference) ?		5k3 alpl armitage beadchip bovinesnp50 bull capn1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Intersection) ?