CATSPER1 and PMF1-BGLAP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CATSPER1	PMF1-BGLAP
Description		cation channel sperm associated 1	PMF1-BGLAP readthrough
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Motile Cilium Monoatomic Ion Channel Complex Sperm Flagellum CatSper Complex Cell Projection Sperm Principal Piece
	Molecular Function	Monoatomic Ion Channel Activity Calcium-activated Cation Channel Activity Voltage-gated Calcium Channel Activity Calcium Channel Activity Protein Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Spermatogenesis Cell Differentiation Flagellated Sperm Motility Monoatomic Ion Transmembrane Transport Transmembrane Transport Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Transmembrane Transport
Pathways		Sperm Motility And Taxes	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs		Bisphenol A diglycidyl ether
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
Interacting Genes		119 interacting genes: ABLIM3 ADAMTSL4 AGR2 AGR3 AJUBA AKAP8L APOA2 ARID5A BEGAIN C11orf16 CARD10 CDPF1 CFAP68 CHIC2 CHRD CPSF7 CTBP2 CYSRT1 EFEMP2 EMD EYA2 FHL5 FRS3 FST GLI1 HNRNPH1 HOXA1 IKZF3 KHDRBS2 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1B LCE1D LCE1E LCE1F LCE2C LCE5A LIMS1 LZTS2 MDFI MTUS2 MYCL NBPF19 NOTCH2NLA PAK5 PDLIM7 PLA2G10 PLAGL2 PLSCR1 PLSCR3 PMF1-BGLAP PTPN21 RFX6 RGS19 RGS20 RIMBP3 RSPO2 SAXO4 SCRG1 SIVA1 SORBS3 SPMIP6 SPRY2 SPRY3 SSC4D TGFB1 TNS2 TRAF2 TRIM27 TRIM42 TRIM8 TRIP6 TSPAN4 VWC2 ZBTB42 ZIM2 ZNF688 ZNF774 ZNF837	2 interacting genes: CATSPER1 TBC1D21
Entrez ID		117144	100527963
HPRD ID		09396
Ensembl ID		ENSG00000175294	ENSG00000260238
Uniprot IDs		Q8NEC5	A0A087WT04 Q6P1K2 U3KQ54
PDB IDs			5LSJ 5LSK 8PPR 8Q5H
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Identical Protein Binding Hair Cycle Protein Binding Cytosol Lead Ion Binding Lung Growth Mercury Ion Binding	Sperm Motility Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Cilium-dependent Cell Motility Cilium Movement Microtubule-based Movement Sperm Mitochondrial Sheath Assembly Male Gamete Generation CatSper Complex Gamete Generation Spermatogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Plasma Membrane To Endosome Transport Calcium-activated Cation Channel Activity Regulation Of Cilium Beat Frequency Microtubule-based Process Developmental Process Involved In Reproduction Sperm Principal Piece Sperm Axoneme Assembly Voltage-gated Calcium Channel Activity Cell Motility Regulation Of Cilium Movement Reproductive Process Regulation Of Microtubule-based Movement Axoneme Assembly Sperm Midpiece Microtubule Bundle Formation Calcium Channel Activity Regulation Of Cilium Assembly Acrosomal Vesicle Sperm Flagellum Monoatomic Ion Channel Complex Monoatomic Ion Channel Activity Cell Differentiation
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