VIPR1 and RAMP3

Number of citations of the paper that reports this interaction (PubMedID 12446722)
0

Data Source:
HPRD (in vitro)

		VIPR1	RAMP3
Description		vasoactive intestinal peptide receptor 1	receptor activity modifying protein 3
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Receptor Complex	Lysosome Plasma Membrane Cell Surface Membrane Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex
	Molecular Function	Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Vasoactive Intestinal Polypeptide Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor 3 Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Adrenomedullin Receptor Signaling Pathway
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors	G alpha (s) signalling events Calcitonin-like ligand receptors
Drugs			Pramlintide
Diseases
GWAS		Bipolar disorder ( 31043756) Cerebrospinal fluid clusterin levels ( 26545630) Hip circumference adjusted for BMI ( 28552196) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)	Hepatic lipid content in extreme obesity ( 25246029)
Interacting Genes		16 interacting genes: ADCYAP1 CALM1 GNAI1 GNAQ GNAS GPRASP1 PFN1 PRDM5 PTMA RAMP1 RAMP2 RAMP3 SCT TINF2 VIP WASL	15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1
Entrez ID		7433	10268
HPRD ID		01890	05517
Ensembl ID		ENSG00000114812	ENSG00000122679
Uniprot IDs		B4DNY6 P32241	A4D2L1 O60896
PDB IDs		1OF2 1OGT 3B3I 3B6S 3DTX 3HCV 5DEF 5DEG 5IB1 5IB2 5IB3 5IB4 5IB5 6VN7 7ALO 8E3Y 8E3Z	6UUS 6UVA 7TZF 8F0K 8F2A 8F2B
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Calcitonin Family Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Guanyl Nucleotide Binding Type 2 Vasoactive Intestinal Polypeptide Receptor Binding Type 1 Vasoactive Intestinal Polypeptide Receptor Binding G-protein Beta/gamma-subunit Complex Binding Response To Prostaglandin E Adrenomedullin Receptor Activity Adrenomedullin Receptor Complex Amylin Receptor Activity Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Heterotrimeric G-protein Complex Adenylate Cyclase Regulator Activity Adenylate Cyclase Activator Activity Adrenomedullin Receptor Signaling Pathway Response To Hormone Coreceptor Activity Regulation Of Peptide Hormone Secretion G Protein Activity Receptor Internalization G Protein-coupled Receptor Binding Peptide Hormone Receptor Binding Activation Of Adenylate Cyclase Activity Regulation Of Signal Transduction Regulation Of Hormone Secretion Regulation Of Hormone Levels Neuropeptide Signaling Pathway Regulation Of Protein Localization Regulation Of Body Fluid Levels Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Acidic PH Hormone Activity Positive Regulation Of Lyase Activity Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Biological Quality Positive Regulation Of Cyclase Activity Regulation Of Metabolic Process G Protein-coupled Serotonin Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Cellular Response To Hormone Stimulus	Intermediate Filament Calcitonin Receptor Activity Calcitonin Gene-related Peptide Receptor Activity Calcitonin Gene-related Peptide Receptor Signaling Pathway Calcitonin Family Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 2 Calcitonin Family Receptor Activity Transmembrane Signaling Receptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 1 Calcitonin Binding Regulation Of Copper Ion Transmembrane Transport G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cellular Response To Sucrose Stimulus Amylin Receptor Complex 3 Extracellular Exosome Biogenesis Adrenomedullin Binding CGRP Receptor Complex Amylin Receptor 3 Signaling Pathway Amylin Receptor Activity SNARE Complex Disassembly Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Proteinase Activated Receptor Binding Adrenomedullin Receptor Complex Adrenomedullin Receptor Activity Amylin Receptor 1 Signaling Pathway Amylin Receptor 2 Signaling Pathway Extracellular Vesicle Biogenesis Positive Regulation Of Extracellular Exosome Assembly Actomyosin Contractile Ring Assembly Keratin Filament G Protein-coupled Receptor Activity Postsynaptic Specialization, Intracellular Component Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Adrenomedullin Receptor Signaling Pathway Amylin Receptor Signaling Pathway Copper Ion Import ATP-dependent Protein Disaggregase Activity Regulation Of Extracellular Exosome Assembly Vascular Associated Smooth Muscle Cell Proliferation Response To Sucrose Response To Disaccharide Copper Ion Transmembrane Transporter Activity Maintenance Of Epithelial Cell Apical/basal Polarity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?